Literature DB >> 459714

Simultaneous mass spectrometric measurement of prostaglandins E1 (PGE1) and PGE2 with a deuterated internal standard.

A Ferretti, V P Flanagan.   

Abstract

The use of (3,3,4,4-2H4)PGE2 as internal standard for the quantitative measurement of PGE1 by gas chromatography-mass spectrometry is reported. A method for the simultaneous analysis of PGE1 and PGE2 is also described. The prostaglandins were analyzed by selected ion monitoring as the methyl ester-trimethylsilyl ether (ME-TMS) derivatives of PGB1 and PGB2, respectively. In all cases, a linear response over the range 1 to 70 ng (2.8 to 198 pmoles) was demonstrated. The use of this procedure is exemplified by its application to the PG analysis of sheep seminal vesicles.

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Year:  1979        PMID： 459714     DOI： 10.1007/bf02533466

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  11 in total

1.  A rapid gas chromatographic-mass spectrometric method for prostaglandin analysis at picomole levels.

Authors:  S Nicosia; G Galli
Journal:  Anal Biochem       Date:  1974-09       Impact factor: 3.365

2.  Methods for quantitative analysis of PGF2 , PGE2, 9 , 11 -dihydroxy-15-keto-prost-5-enoic acid and 9 , 11 , 15-trihydroxy-prost-5-enoic acid from body fluids using deuterated carriers and gas chromatography--mass spectrometry.

Authors:  K Gréen; E Granström; B Samuelsson; U Axen
Journal:  Anal Biochem       Date:  1973-08       Impact factor: 3.365

3.  Quantitative determination of prostaglandins.

Authors:  B J Sweetman; J C Frölich; J T Watson
Journal:  Prostaglandins       Date:  1973-01

4.  Method for the measurement of prostaglandin F2alpha in biological fluids by gas chromatography-mass spectrometry.

Authors:  R W Kelly
Journal:  Anal Chem       Date:  1973-10       Impact factor: 6.986

5.  Modified prostaglandins as internal standards for quantitative analysis of prostaglandins of the E series by combined gas chromatography-mass spectrometry.

Authors:  B S Middleditch; D M Desiderio
Journal:  Prostaglandins       Date:  1973-09

6.  Gas chromatography--mass spectrometry of O-methyloxime derivatives of prostaglandins.

Authors:  K Gréen
Journal:  Chem Phys Lipids       Date:  1969-09       Impact factor: 3.329

7.  Quantitative gas chromatography of prostaglandin E1 at the Nanogram level: use of deuterated carrier and multiple-ion analyzer.

Authors:  B Samuelsson; M Hamberg; C C Sweeley
Journal:  Anal Biochem       Date:  1970-11       Impact factor: 3.365

8.  Utility of d4-PGE2 as an internal standard to quantify endogenous levels of PGE1, PGE2, 19OH PGE1 and 19OH PGE2 in human seminal fluid by GC-MS-SIM.

Authors:  D L Perry; D M Desiderio
Journal:  Prostaglandins       Date:  1977-10

9.  Radioimmunoassay of prostaglandins E1, E2, and F2alpha in unextracted plasma, serum and myocardium.

Authors:  E J McCosh; D L Meyer; J Dupont
Journal:  Prostaglandins       Date:  1976-10

10.  Radioimmunoassay of PGE and an approach to the specific measurement of PGE1.

Authors:  D E Van Orden; D B Farley; C J Clancey
Journal:  Prostaglandins       Date:  1977-03
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  3 in total

1.  Quantitative measurement of prostaglandins E2 and E2 by selected ion monitoring.

Authors:  A Ferretti; V P Flanagan; J M Roman
Journal:  Lipids       Date:  1982-11       Impact factor: 1.880

2.  Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2.

Authors:  B F McAdam; F Catella-Lawson; I A Mardini; S Kapoor; J A Lawson; G A FitzGerald
Journal:  Proc Natl Acad Sci U S A       Date:  1999-01-05       Impact factor: 11.205

3.  Identification and quantification of prostaglandin E3 in renal medullary tissue of three strains of rats fed fish oil.

Authors:  A Ferretti; N W Schoene; V P Flanagan
Journal:  Lipids       Date:  1981-11       Impact factor: 1.880
  3 in total

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