| Literature DB >> 4595940 |
Abstract
Pancreatic tissue from hamsters inoculated with a virulent strain of Venezuelan equine encephalomyelitis virus (VEE) was studied sequentially with fluorescent antibody, light and electron microscopic technics. Progressive viral growth and cellular necrosis in the pancreas were demonstrated. Pancreatic infection resulted from both viremia and direct extension from the spleen across contaminated serosal planes. Mature viruses traversed the endothelium within endothelial vesicles and were associated with acinar as well as islet cells.Entities:
Mesh:
Year: 1974 PMID: 4595940 PMCID: PMC1910833
Source DB: PubMed Journal: Am J Pathol ISSN: 0002-9440 Impact factor: 4.307