Literature DB >> 4594320

Ineffectiveness of an oral killed typhoid vaccine in a field trial.

C S Chuttani, K Prakash, A Vergese, P Gupta, R K Chawla, V Grover, D S Agarwal.   

Abstract

A field trial was carried out with a vaccine containing 300x10(9) killed S. typhi (strain Ty58) per tablet. A total of 12 564 children aged 1-15 years were given 3 tablets of the vaccine or a placebo at the rate of one tablet on each of 3 consecutive days. The results indicated that the vaccine, in its present form and at this dosage, gives no protection.

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Year:  1973        PMID: 4594320      PMCID: PMC2483068     

Source DB:  PubMed          Journal:  Bull World Health Organ        ISSN: 0042-9686            Impact factor:   9.408


  1 in total

1.  Effectiveness of oral killed typhoid vaccine.

Authors:  C S Chuttani; K Prakash; A Vergese; U Sharma; P Singha; B G Ray
Journal:  Bull World Health Organ       Date:  1971       Impact factor: 9.408

  1 in total
  5 in total

1.  TTSS2-deficient hha mutant of Salmonella Typhimurium exhibits significant systemic attenuation in immunocompromised hosts.

Authors:  Vikalp Vishwakarma; Niladri Bhusan Pati; Shilpa Ray; Susmita Das; Mrutyunjay Suar
Journal:  Virulence       Date:  2014-01-08       Impact factor: 5.882

Review 2.  Advances in vaccines for typhoid fever.

Authors:  A Gupta; S Jalla; S Sazawal; M K Bhan
Journal:  Indian J Pediatr       Date:  1994 Jul-Aug       Impact factor: 1.967

Review 3.  Typhoid immunisation.

Authors:  O P Ghai; V K Paul
Journal:  Indian J Pediatr       Date:  1984 Jan-Feb       Impact factor: 1.967

Review 4.  Vaccines for preventing typhoid fever.

Authors:  Rachael Milligan; Mical Paul; Marty Richardson; Ami Neuberger
Journal:  Cochrane Database Syst Rev       Date:  2018-05-31

5.  Evaluation of Salmonella enterica serovar Typhimurium TTSS-2 deficient fur mutant as safe live-attenuated vaccine candidate for immunocompromised mice.

Authors:  Vikalp Vishwakarma; Niladri Bhusan Pati; Himanshu Singh Chandel; Sushree Sangeeta Sahoo; Bhaskar Saha; Mrutyunjay Suar
Journal:  PLoS One       Date:  2012-12-17       Impact factor: 3.240

  5 in total

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