Literature DB >> 459373

Activity of procollagen-prolyl-hydroxylase and N-acetyl-beta-glucosaminidase in liver biopsies from patients with chronic liver diseases.

G Pott, G Eberhardt, U Gerlach.   

Abstract

In 5 mg of liver tissue obtained by needle biopsy from patients with chronic liver diseases, activity of both Procollagen-prolyl-hydroxylase and N-Acetyl-beta-glucosaminidase was measured. The activity of both enzymes increased due to the activity of fibrosis, but prolylhydroxylase increased more. The relation of these two enzyme activities in the development of liver fibrosis is discussed.

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Year:  1979        PMID: 459373     DOI: 10.1007/bf01491138

Source DB:  PubMed          Journal:  Klin Wochenschr        ISSN: 0023-2173


  14 in total

1.  [A colorimetric routine methods for determination of small quantities of proteins in body fluids and tissues].

Authors:  E BOHLE; H FISCHER
Journal:  Klin Wochenschr       Date:  1953-09-01

2.  [Consideration of the mesenchyme-reaction in patients with cronical liver-diseases (author's transl)].

Authors:  G Pott; G Eberhardt; U Gerlach
Journal:  Z Gastroenterol       Date:  1978-01       Impact factor: 2.000

Review 3.  Prolyl hydroxylase.

Authors:  G J Cardinale; S Udenfriend
Journal:  Adv Enzymol Relat Areas Mol Biol       Date:  1974

4.  Serum hyaluronidase activity in chronic liver damage.

Authors:  N Nakamura; N Iwabori; T Koizumi
Journal:  Clin Chim Acta       Date:  1970-01       Impact factor: 3.786

Review 5.  The biosynthesis of collagen. 1.

Authors:  M E Grant; D J Prockop
Journal:  N Engl J Med       Date:  1972-01-27       Impact factor: 91.245

6.  Prolyl hydroxylase activity in normal and diseased human liver.

Authors:  G C Fuller; J C Nolan
Journal:  Proc Soc Exp Biol Med       Date:  1976-01

7.  N-acetyl-beta-hexosaminidase: role in the degradation of glycosaminoglycans.

Authors:  J N Thompson; A C Stoolmiller; R Matalon; A Dorfman
Journal:  Science       Date:  1973-08-31       Impact factor: 47.728

8.  Activities of prolyl hydroxylase, lysyl hydroxylase, collagen galactosyltransferase and collagen glucosyltransferase in the liver of rats with hepatic injury.

Authors:  J Risteli; K I Kivirikko
Journal:  Biochem J       Date:  1974-10       Impact factor: 3.857

9.  Collagen proline hydroxylase activity and 35S sulphate uptake in human liver biopsies.

Authors:  J O McGee; R S Patrick; M C Rodger; C M Luty
Journal:  Gut       Date:  1974-04       Impact factor: 23.059

10.  Isoenzymes of N-acetyl-beta-glucosaminidase from human liver and serum: separation by electrofocusing in thin layers of polyacrylamide gel.

Authors:  G Pott; D Chi-Boesler; U Gerlach
Journal:  J Clin Chem Clin Biochem       Date:  1978-01
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  1 in total

Review 1.  Connective tissue components of the normal and fibrotic human liver. II. Clinical aspects.

Authors:  G Pott; J Rauterberg; B Voss; U Gerlach
Journal:  Klin Wochenschr       Date:  1982-01-04
  1 in total

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