Literature DB >> 4588

Cyanide intoxication in the rat: physiological and neuropathological aspects.

J B Brierley, A W Brown, J Calverley.   

Abstract

Sodium cyanide was given to rats by intravenous infusion at a rate that would avert apnoea (the first sign of overdosage) in the majority. There was full physiological monitoring in a group under anaesthesia and more limited monitoring in an unanaesthetized group. White matter was damaged in six animals and grey matter additionally in only one. It was concluded that cyanide can damage neurones only through the medium of secondary effects on circulation and respiration.

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Year:  1976        PMID: 4588      PMCID: PMC492237          DOI: 10.1136/jnnp.39.2.129

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN: 0022-3050            Impact factor:   10.154


  10 in total

1.  Experimental cyanide encephalopathy.

Authors:  S LEVINE; W STYPULKOWSKI
Journal:  AMA Arch Pathol       Date:  1959-03

2.  Metabolic and electroencephalographic effects of hyperventilation. Experimental studies of brain oxygen and carbon dioxide tension, pH, EEG and blood flow during hyperventilation.

Authors:  J S MEYER; F GOTOH
Journal:  Arch Neurol       Date:  1960-11

3.  Cyanide encephalopathy produced by intravenous route.

Authors:  S LEVINE; E J WENK
Journal:  J Nerv Ment Dis       Date:  1959-09       Impact factor: 2.254

4.  Brain metabolism in vivo; the distribution of lesions caused by cyanide poisoning, insulin hypoglycemia, asphyxia in nitrogen and fluoroacetate poisoning in rats.

Authors:  S P HICKS
Journal:  AMA Arch Pathol       Date:  1950-02

5.  Tetany: quantitative interrelationships between calcium and alkalosis.

Authors:  J W Edmondson; R E Brashear; T K Li
Journal:  Am J Physiol       Date:  1975-04

6.  The effect of marked hyperventilation upon tissue levels of NADH, lactate, pyruvate, phosphocreatine, and adenosine phosphates of rat brain.

Authors:  L Granholm; L Lukjanova; B K Siesjö
Journal:  Acta Physiol Scand       Date:  1969 Sep-Oct

7.  The earliest alterations in rat neurones and astrocytes after anoxia-ischaemia.

Authors:  A W Brown; J B Brierley
Journal:  Acta Neuropathol       Date:  1973       Impact factor: 17.088

8.  The nature, distribution and earliest stages of anoxic-ischaemic nerve cell damage in the rat brain as defined by the optical microscope.

Authors:  A W Brown; J B Brierley
Journal:  Br J Exp Pathol       Date:  1968-04

9.  Reduction of increased intracranial pressure. Comparison between hyperbaric oxygen and hyperventilation.

Authors:  J D Miller; I M Ledingham
Journal:  Arch Neurol       Date:  1971-03

10.  Effect of injury on shivering thermogenesis in the rat.

Authors:  H B Stoner
Journal:  J Physiol       Date:  1971-05       Impact factor: 5.182

  10 in total
  8 in total

Review 1.  Experimental hypoxic brain damage.

Authors:  J B Brierley
Journal:  J Clin Pathol Suppl (R Coll Pathol)       Date:  1977

2.  Comparison of cobinamide to hydroxocobalamin in reversing cyanide physiologic effects in rabbits using diffuse optical spectroscopy monitoring.

Authors:  Matthew Brenner; Sari B Mahon; Jangwoen Lee; Jae Kim; David Mukai; Seth Goodman; Kelly A Kreuter; Rebecca Ahdout; Othman Mohammad; Vijay S Sharma; William Blackledge; Gerry R Boss
Journal:  J Biomed Opt       Date:  2010 Jan-Feb       Impact factor: 3.170

3.  Is there an energy conservation "system" in brain that protects against the consequences of energy depletion?

Authors:  T Pazdernik; R Cross; S Nelson; Y Kamijo; F Samson
Journal:  Neurochem Res       Date:  1994-11       Impact factor: 3.996

4.  Correlation of morphologic brain lesions with physiologic alterations and blood-brain barrier impairment in 3-nitropropionic acid toxicity in rats.

Authors:  B F Hamilton; D H Gould
Journal:  Acta Neuropathol       Date:  1987       Impact factor: 17.088

5.  Noninvasive in vivo monitoring of cyanide toxicity and treatment using diffuse optical spectroscopy in a rabbit model.

Authors:  Jangwoen Lee; Kelly A Keuter; Jae Kim; Andrew Tran; Amit Uppal; David Mukai; Sari Brenner Mahon; Leopoldo C Cancio; Andriy Batchinsky; Bruce J Tromberg; Matthew Brenner
Journal:  Mil Med       Date:  2009-06       Impact factor: 1.437

6.  Intramuscular cobinamide sulfite in a rabbit model of sublethal cyanide toxicity.

Authors:  Matthew Brenner; Jae G Kim; Sari B Mahon; Jangwoen Lee; Kelly A Kreuter; William Blackledge; David Mukai; Steve Patterson; Othman Mohammad; Vijay S Sharma; Gerry R Boss
Journal:  Ann Emerg Med       Date:  2010-01-04       Impact factor: 5.721

7.  A study of experimental cyanide encephalopathy in the acute phase--physiological and neuropathological correlation.

Authors:  N Funata; S Y Song; R Okeda; M Funata; F Higashino
Journal:  Acta Neuropathol       Date:  1984       Impact factor: 17.088

8.  Circulatory Failure During Noninhaled Forms of Cyanide Intoxication.

Authors:  Philippe Haouzi; Nicole Tubbs; Matthew D Rannals; Annick Judenherc-Haouzi; Larry A Cabell; Joe A McDonough; Takashi Sonobe
Journal:  Shock       Date:  2017-03       Impact factor: 3.454

  8 in total

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