Literature DB >> 458164

Solid-phase radioimmunoassay for the detection of antibodies to collagen.

R B Clague, R A Brown, J B Weiss, P J Holt.   

Abstract

A solid-phase radioimmunoassay has been developed using polystyrene tubes for the detection of class-specific antibodies to collagen. The optimal conditions for the adsorption of collagen onto the tubes, followed by incubation with the antisera and finally the radiolabelled antibody to the class-specific antibody are described. Studies carried out on antisera raised in rats and rabbits using this assay confirm its sensitivity and applicability.

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Year:  1979        PMID： 458164     DOI： 10.1016/0022-1759(79)90236-9

Source DB:  PubMed          Journal:  J Immunol Methods        ISSN： 0022-1759            Impact factor:   2.303


  6 in total

1.  Native type II collagen-induced arthritis in the rat. III. Relationship between the cellular immune response to native type II collagen and arthritis.

Authors:  W A Ofosu-Appiah; K Morgan; P J Lennox Holt
Journal:  Ann Rheum Dis       Date:  1983-06       Impact factor: 19.103

2.  1 Alpha 2 alpha 3 alpha collagen is arthritogenic.

Authors:  K Morgan; H B Evans; S A Firth; M N Smith; S Ayad; J B Weiss; P J Lennox Holt
Journal:  Ann Rheum Dis       Date:  1983-12       Impact factor: 19.103

3.  The absence of antibodies to type II collagen in established adjuvant arthritis in rats.

Authors:  F DeLustro; R P Carlson; L J Datko; B DeLustro; A J Lewis
Journal:  Agents Actions       Date:  1984-06

4.  Serum antibodies to type II collagen in rheumatoid arthritis: comparison of 6 immunological methods and clinical features.

Authors:  R B Clague; S A Firth; P J Holt; J Skingle; C L Greenbury; M Webley
Journal:  Ann Rheum Dis       Date:  1983-10       Impact factor: 19.103

5.  Incidence of serum antibodies to native type I and type II collagens in patients with inflammatory arthritis.

Authors:  R B Clague; M J Shaw; P J Holt
Journal:  Ann Rheum Dis       Date:  1980-06       Impact factor: 19.103

6.  Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates.

Authors:  P H Wooley; H S Luthra; J M Stuart; C S David
Journal:  J Exp Med       Date:  1981-09-01       Impact factor: 14.307
  6 in total

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