Literature DB >> 4581052

Methyltetrahydrofolic acid mediates N- and O-methylation of biogenic amines.

S P Banerjee, S H Snyder.   

Abstract

A variety of mammalian and avian tissues N- and O-methylate indoleamines and phenylethylamines, with methyltetrahydrofolic acid as the methyl donor. Because it is considerably more efficient than S-adenosylmethionine, methyltetrahydrofolic acid may be the natural methyl donor in this reaction. With methyltetrahydrofolic acid, serotonin is O-methylated to 5-methoxytryptamine, a novel indoleamine in mammalian brain.

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Year:  1973        PMID： 4581052     DOI： 10.1126/science.182.4107.74

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  5 in total

Review 1.  Resistance to cytostatic drugs at the cellular level.

Authors:  C P Vendrik; J J Bergers; W H De Jong; P A Steerenberg
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

2.  Ontogenetic development of a 5-methyltetrahydrofolate requiring enzyme in rats and mice.

Authors:  P Laduron; P F Janssen; G Aerts; J Leysen
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1975       Impact factor: 3.000

3.  Neurochemical investigations of the interaction of N,N-dimethyltryptamine with dopaminergic system in rat brain.

Authors:  P C Waldmeier; L Maître
Journal:  Psychopharmacology (Berl)       Date:  1977-04-29       Impact factor: 4.530

4.  Serotonin uptake by blood platelets of acute schizophrenic patients.

Authors:  I Modai; A Rotman; H Munitz; S Tjano; H Wijsenbeek
Journal:  Psychopharmacology (Berl)       Date:  1979-08-08       Impact factor: 4.530

Review 5.  Folates, folic acid and preconception care - a review.

Authors:  Simon H House; John Aa Nichols; Sarah Rae
Journal:  JRSM Open       Date:  2021-05-13
  5 in total

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