Literature DB >> 4579481

Peroxidase mediated antimicrobial activities of alveolar macrophage granules.

B B Paul, R R Strauss, R J Selvaraj, A J Sbarra.   

Abstract

The 20,000g pellet obtained by centrifugation of a homogenate of rabbit alveolar macrophages has antibacterial activity in the presence of a hydrogen peroxide-generating system and iodide. Peroxidase activity has been demonstrated in this fraction. Addition of 3-amino-1,2,4-triazole diminished the antibacterial activity of the pellet-hydrogen peroxide-iodide system.

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Year:  1973        PMID: 4579481     DOI: 10.1126/science.181.4102.849

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  3 in total

1.  Bactericidal mechanisms in rabbit alveolar macrophages: evidence against peroxidase and hydrogen peroxide bactericidal mechanisms.

Authors:  W D Biggar; S Buron; B Holmes
Journal:  Infect Immun       Date:  1976-07       Impact factor: 3.441

2.  Myeloperoxidase-hydrogen peroxide-chloride antimicrobial system: effect of exogenous amines on antibacterial action against Escherichia coli.

Authors:  E L Thomas
Journal:  Infect Immun       Date:  1979-07       Impact factor: 3.441

3.  Fungicidal activity of rabbit alveolar and peritoneal macrophages against Candida albicans.

Authors:  R I Lehrer; L G Ferrari; J Patterson-Delafield; T Sorrell
Journal:  Infect Immun       Date:  1980-06       Impact factor: 3.441

  3 in total

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