Literature DB >> 4577839

Treatment of chronic gastric ulcer with carbenoxolone and gefarnate: a comparative trial.

M J Langman, D R Knapp, E J Wakley.   

Abstract

In 68 patients with chronic gastric ulcer treated in an outpatient clinical trial with either carbenoxolone or gefarnate ulcer healing was consistently greater during carbenoxolone treatment, even though the dose of gefarnate was ultimately increased to four times that recommended. One-third of the patients receiving carbenoxolone gained weight rapidly and unexpectedly, and were given diuretic treatment, compared with two of the 35 patients receiving gefarnate, neither of whom developed clinical oedema.

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Year:  1973        PMID: 4577839      PMCID: PMC1586515          DOI: 10.1136/bmj.3.5871.84

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  4 in total

1.  TREATMENT OF GASTRIC ULCER WITH CARBENOXOLONE SODIUM AND OESTROGENS.

Authors:  R DOLL; I D HILL; C F HUTTON
Journal:  Gut       Date:  1965-02       Impact factor: 23.059

2.  Treatment of gastric ulcer with carbenoxolone: antagonistic effect of spironolactone.

Authors:  R Doll; M J Langman; H H Shawdon
Journal:  Gut       Date:  1968-02       Impact factor: 23.059

3.  Carbenoxolone sodium in the treatment of gastric ulcer with special reference to side-effects.

Authors:  A G Turpie; T J Thomson
Journal:  Gut       Date:  1965-12       Impact factor: 23.059

4.  [Endoscopic study of clinical trials of geranyl farnesylacetate].

Authors:  C T Da Grada; O Greco; P Campagnoli
Journal:  Minerva Gastroenterol       Date:  1967 Oct-Dec
  4 in total
  8 in total

Review 1.  Drugs in the treatment of gastric and duodenal ulcer.

Authors:  M J Langman
Journal:  Drugs       Date:  1977-08       Impact factor: 9.546

Review 2.  Treatment of uncomplicated gastric ulcer.

Authors:  W D Davis
Journal:  Am J Dig Dis       Date:  1976-02

3.  Carbenoxolone sodium: its role in ulcer healing.

Authors:  M J Langman
Journal:  Drugs       Date:  1976       Impact factor: 9.546

Review 4.  Current therapy in peptic ulcer.

Authors:  I N Marks
Journal:  Drugs       Date:  1980-10       Impact factor: 9.546

5.  The anti-ulcerogenic activity of the unripe plantain banana (Musa species).

Authors:  R Best; D A Lewis; N Nasser
Journal:  Br J Pharmacol       Date:  1984-05       Impact factor: 8.739

6.  Controlled comparison of cimetidine and carbenoxolone sodium in gastric ulcer.

Authors:  S J La Brooy; R H Taylor; R H Hunt; P L Golding; J M Laidlaw; R G Chapman; R E Pounder; S H Vincent; D G Colin-Jones; G J Milton-Thompson; J J Misiewicz
Journal:  Br Med J       Date:  1979-05-19

7.  Medical treatment of gastric and duodenal ulcer.

Authors:  J H Baron
Journal:  Klin Wochenschr       Date:  1976-10-01

Review 8.  Carbenoxolone: a review of its pharmacological properties and therapeutic efficacy in peptic ulcer disease.

Authors:  R M Pinder; R N Brogden; P R Sawyer; T M Speight; R Spencer; G S Avery
Journal:  Drugs       Date:  1976       Impact factor: 9.546

  8 in total

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