| Literature DB >> 4574848 |
Abstract
Guinea pigs injected with rabbit tubular basement membranes and Freund's adjuvant develop progressive renal cortical tubulointerstitial disease and deposit autoantibodies in their cortical tubular basement membranes. The identical, even fatal, disease may be produced in normal guinea pigs by a single intraperitoneal injection of serums obtained from guinea pigs with this tubulointerstitial disease, provided such serums contain sufficient amounts of autoantibodies against tubular basement membranes.Entities:
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Year: 1973 PMID: 4574848 DOI: 10.1126/science.180.4089.966
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728