Literature DB >> 4574848

Transfer of experimental autoimmune renal cortical tubular and interstitial disease in guinea pigs by serum.

R W Steblay, U Rudofsky.   

Abstract

Guinea pigs injected with rabbit tubular basement membranes and Freund's adjuvant develop progressive renal cortical tubulointerstitial disease and deposit autoantibodies in their cortical tubular basement membranes. The identical, even fatal, disease may be produced in normal guinea pigs by a single intraperitoneal injection of serums obtained from guinea pigs with this tubulointerstitial disease, provided such serums contain sufficient amounts of autoantibodies against tubular basement membranes.

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Year:  1973        PMID: 4574848     DOI: 10.1126/science.180.4089.966

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  11 in total

1.  Methicillin induced interstitial nephritis.

Authors: 
Journal:  West J Med       Date:  1975-11

Review 2.  Immunologically mediated lesions of kidney tubules and interstitium in laboratory animals and in man.

Authors:  J R Brentjens; B Noble; G A Andres
Journal:  Springer Semin Immunopathol       Date:  1982

3.  Transplacental transmission of antibodies to tubular basement membrane in guinea-pigs with autoimmune tubulointerstitial nephritis.

Authors:  B Albini; M Milgrom; B Noble; C Albini; E Ossi; G A Andres
Journal:  Clin Exp Immunol       Date:  1984-04       Impact factor: 4.330

4.  Animal model of human disease: anti-tubular-basement-membrane-antibody tubulointerstitial nephritis.

Authors:  R W Steblay
Journal:  Am J Pathol       Date:  1979-12       Impact factor: 4.307

5.  Studies on the pathogenesis of experimental autoimmune renal tubulointerstitial disease in guinea-pigs. IV. failure to inhibit mononuclear cell accumulation with niridazole.

Authors:  U H Rudofsky; B Pollara
Journal:  Clin Exp Immunol       Date:  1977-03       Impact factor: 4.330

6.  Studies on the pathogenesis of experimental anti-tubular basement membrane nephritis in the guinea pig.

Authors:  M J Van Zwieten; A K Bhan; R T McCluskey; A B Collins
Journal:  Am J Pathol       Date:  1976-06       Impact factor: 4.307

7.  Structural observations on epithelioid and giant cells in experimental autoimmune tubulointerstitial nephritis in guinea pigs.

Authors:  G A Andres; C Szymanski; B Albini; J Brentjens; M Milgrom; B Noble; E Ossi; R Steblay
Journal:  Am J Pathol       Date:  1979-07       Impact factor: 4.307

8.  Studies on the pathogenesis of experimental autoimmune renal tubulointerstitial disease in guinea-pigs. III. The role of adjuvants in the induction of disease.

Authors:  U H Rudofsky
Journal:  Clin Exp Immunol       Date:  1976-09       Impact factor: 4.330

Review 9.  Tubulointerstitial nephritis.

Authors:  C L Jones; A A Eddy
Journal:  Pediatr Nephrol       Date:  1992-11       Impact factor: 3.714

10.  Autoimmune interstitial nephritis induced in inbred mice. Analysis of mouse tubular basement membrane antigen and genetic control of immune response to it.

Authors:  S Ueda; M Wakashin; Y Wakashin; H Yoshida; R Azemoto; K Iesato; T Mori; Y Mori; M Ogawa; K Okuda
Journal:  Am J Pathol       Date:  1988-08       Impact factor: 4.307

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