Literature DB >> 4573394

Pronase effect on pancreatic beta cell secretion and morphology.

L Orci, M Amherdt, J C Henquin, A E Lambert, R H Unger, A E Renold.   

Abstract

Pronase at low concentration (4 micrograms per milliliter) produces a reversible increase of glucose-stimulated insulin release in isolated islets of Langerhans. Pronase also affects the ultrastructure of the beta cells by inducing extensive development of tight junctions as well as the accumulation of secretory product within the extracellular spaces.

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Year:  1973        PMID： 4573394     DOI： 10.1126/science.180.4086.647

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  24 in total

Review 1.  Claudins and the modulation of tight junction permeability.

Authors:  Dorothee Günzel; Alan S L Yu
Journal:  Physiol Rev       Date:  2013-04       Impact factor: 37.312

2.  Ultrastructural and morphometric studies of delta cells in pancreatic islets from C57BL/Ks diabetes mice.

Authors:  E H Leiter; D A Gapp; J J Eppig; D L Coleman
Journal:  Diabetologia       Date:  1979-11       Impact factor: 10.122

Review 3.  A portrait of the pancreatic B-cell. The Minkowski Award Lecture delivered on July 19, 1973, during the 8th Congress of the International Diabetes Federation, held in Brussels, Belgium.

Authors:  L Orci
Journal:  Diabetologia       Date:  1974-06       Impact factor: 10.122

Review 4.  Islet cell interactions with pancreatic B-cells.

Authors:  D Pipeleers
Journal:  Experientia       Date:  1984-10-15

5.  A method for the purification of single A, B and D cells and for the isolation of coupled cells from isolated rat islets.

Authors:  D G Pipeleers; M A Pipeleers-Marichal
Journal:  Diabetologia       Date:  1981-06       Impact factor: 10.122

6.  Exocrine pancreas under experimental conditions. III. Membrane and cell junctions in isolated acinar cells.

Authors:  J Metz; W G Forssman; S Ito
Journal:  Cell Tissue Res       Date:  1977-02-14       Impact factor: 5.249

7.  Cell surface modifications in the epithelium of rat ventral prostate during adaptation to in vitro conditions: an ultrastructural study.

Authors:  F B Merk; P W Kwan; S Spilman; L Terracio; W H Douglas
Journal:  In Vitro       Date:  1984-03

8.  Exocrine pancreas under experimental conditions. IV. Alterations of intercellular junctions between acinar cells following pancreatic duct ligation.

Authors:  J Metz; M Merlo; H Billich; W G Forssmann
Journal:  Cell Tissue Res       Date:  1978-01-17       Impact factor: 5.249

9.  Nonenzymic in vitro isolation of perinatal islets of Langerhans.

Authors:  O D Hegre; S Marshall; B A Schulte; G E Hickey; F Williams; R L Sorenson; J R Serie
Journal:  In Vitro       Date:  1983-08

10.  The gastric mucosal barrier: tight junction structure in gastritis and ulcer biopsies.

Authors:  Z Posalaky; I Posalaky; D McGinley; R A Meyer
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1989
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