Literature DB >> 4573316

Interaction between levodopa and methyldopa.

F B Gibberd, E Small.   

Abstract

The interaction between methyldopa and levodopa was studied in 18 patients with Parkinsonism. Together they produced a fall in blood pressure in doses which when given alone had no effect or only a slight hypotensive effect. Severe hypotension never occurred. It is reasonable to give methyldopa to hypertensive patients on levodopa but the regimen should be initiated in hospital.

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Year:  1973        PMID: 4573316      PMCID: PMC1589055          DOI: 10.1136/bmj.2.5858.90

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  6 in total

1.  PARKINSONISM ASSOCIATED WITH ALPHA-METHYLDOPA THERAPY.

Authors:  M J PEASTON
Journal:  Br Med J       Date:  1964-07-18

2.  Parkinsonism occurring with methyldopa treatment.

Authors:  B M GRODEN
Journal:  Br Med J       Date:  1963-04-13

3.  Autoimmunity in patients treated with levodopa.

Authors:  G C Cotzias; P S Papavasiliou
Journal:  JAMA       Date:  1969-02-17       Impact factor: 56.272

4.  Levodopa, Parkinson's disease, and hypotension.

Authors:  F H McDowell; J E Lee
Journal:  Ann Intern Med       Date:  1970-05       Impact factor: 25.391

5.  Use of levodopa with other drugs.

Authors:  K R Hunter; G M Stern; D R Laurence
Journal:  Lancet       Date:  1970-12-19       Impact factor: 79.321

6.  Renin-aldosterone system in Parkinson's disease.

Authors:  A Barbeau; L Gillo-Joffroy; R Boucher; W Nowaczynski; J Genest
Journal:  Science       Date:  1969-07-18       Impact factor: 47.728

  6 in total
  1 in total

1.  Antiparkinsonian Agents : Clinically Significant Drug Interactions and Adverse Effects, and Their Management.

Authors:  A Dalvi; B Ford
Journal:  CNS Drugs       Date:  1998-04       Impact factor: 5.749

  1 in total

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