Literature DB >> 4573315

Clinical and laboratory double-blind investigation on effect of fibrinolytic therapy in patients with cutaneous vasculitis.

B Dodman, W J Cunliffe, B E Roberts, R Sibbald.   

Abstract

The effects of phenformin and ethyloestrenol and phenformin and stanozolol on the clinical state, plasma fibrinolytic activity, and fibrinogen-fibrin-related antigen (F.R.-antigen) were compared with placebo in 13 patients with cutaneous vasculitis. Eight patients showed considerable clinical improvement when taking phenformin and an anabolic steroid; an impaired fibrinolytic activity before treatment favoured clinical improvement.

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Year:  1973        PMID: 4573315      PMCID: PMC1589113          DOI: 10.1136/bmj.2.5858.82

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  11 in total

Review 1.  The role of immune complexes and complement in tissue injury.

Authors:  C G Cochrane
Journal:  J Allergy       Date:  1968-09

2.  The association between cutaneous vasculitis and decreased blood fibrinolytic activity.

Authors:  W J Cunliffe; I S Menon
Journal:  Br J Dermatol       Date:  1971-02       Impact factor: 9.302

3.  Coagulation and fibrinolysis in chronic panniculitis.

Authors:  S Isacson; F Linell; H Möller; I M Nilsson
Journal:  Acta Derm Venereol       Date:  1970       Impact factor: 4.437

4.  Introduction of intravascular coagulation and focal tissue necrosis in rats by administration of anti-connective tissue antibodies.

Authors:  D H Katz; E R Unanue; F J Dixon
Journal:  Am J Pathol       Date:  1968-11       Impact factor: 4.307

5.  Fibrinolytic and defibrinating effect of phenformin plus ethyloestrenol in vivo.

Authors:  G R Fearnley; R Chakrabarti; J F Evans
Journal:  Lancet       Date:  1969-05-03       Impact factor: 79.321

6.  Fibrinogen titre, fibrinolysis and platelet stickiness correlated with capillary bleeding or block in the skin.

Authors:  A K Kurban; T J Ryan
Journal:  Trans St Johns Hosp Dermatol Soc       Date:  1969

7.  The origin of fibrin breakdown products and the interpretation of their appearance in the circulation.

Authors:  M J Gallimore; H M Tyler; J T Shaw
Journal:  J Clin Pathol       Date:  1972-03       Impact factor: 3.411

8.  Fibrinolytic activity and haemagglutination inhibition immunoassays.

Authors:  J Gormsen
Journal:  Scand J Haematol       Date:  1970

9.  Quantitative estimation of split products of fibrinogen in human serum, relation to diagnosis and treatment.

Authors:  C Merskey; G J Kleiner; A J Johnson
Journal:  Blood       Date:  1966-07       Impact factor: 22.113

10.  Spontaneous thymoma, polymyositis, and serum-autoantibodies to striated muscle in the rodent, subgenus Praomys (Mastomys) natalensis. Similarities to thymoma with myasthenia gravis in man.

Authors:  A J Strauss; K C Snell; B J Duntley; E J Soban; H L Stewart
Journal:  Lancet       Date:  1968-05-25       Impact factor: 79.321

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  3 in total

1.  Effect of fibrinolytic treatment in malignant atrophic papulosis.

Authors:  T J Delaney; M M Black
Journal:  Br Med J       Date:  1975-08-16

2.  Prophylactic agents for thrombosis.

Authors:  P A Castaldi
Journal:  Drugs       Date:  1975       Impact factor: 9.546

3.  Cutaneous angiitis.

Authors:  P W Copeman
Journal:  J R Coll Physicians Lond       Date:  1975-01
  3 in total

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