Literature DB >> 4572723

In vivo complementation between wild-type and mutant -galactosidase in Escherichia coli.

B G Hall.   

Abstract

A comparison of the specific activity of wild-type beta-galactosidase synthesized in a lacZ(-)/lacZ(+) heterogenote has shown that there is 60% more activity in the heterogenote's enzyme than can be accounted for by wild-type subunits alone. It is concluded that wild type beta-galactosidase subunits can complement mutant subunits.

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Year:  1973        PMID： 4572723      PMCID： PMC251786          DOI： 10.1128/jb.114.1.448-450.1973

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  7 in total

1.  THE THEORY OF INTER-ALLELIC COMPLEMENTATION.

Authors:  F H CRICK; L E ORGEL
Journal:  J Mol Biol       Date:  1964-01       Impact factor: 5.469

2.  Defective translation in RC - cells.

Authors:  B Hall; J Gallant
Journal:  Nat New Biol       Date:  1972-05-31

3.  Antibody-mediated activation of a defective beta-D-galactosidase extracted from an Escherichia coli mutant.

Authors:  M B Rotman; F Celada
Journal:  Proc Natl Acad Sci U S A       Date:  1968-06       Impact factor: 11.205

4.  Subunit interaction of a temperature-sensitive alcohol dehydrogenase mutant in maize.

Authors:  D Schwartz
Journal:  Genetics       Date:  1971-04       Impact factor: 4.562

5.  Nonsense mutants and polarity in the lac operon of Escherichia coli.

Authors:  W A Newton; J R Beckwith; D Zipser; S Brenner
Journal:  J Mol Biol       Date:  1965-11       Impact factor: 5.469

6.  Hybrid enzyme molecules reconstituted from mixtures of wild-type and mutant Escherichia coli -galactosidase.

Authors:  F Melchers; W Messer
Journal:  J Mol Biol       Date:  1971-10-28       Impact factor: 5.469

7.  The number of sex-factors per chromosome in Escherichia coli.

Authors:  R Frame; J O Bishop
Journal:  Biochem J       Date:  1971-01       Impact factor: 3.857
  7 in total
  4 in total

Review 1.  Laboratory-directed protein evolution.

Authors:  Ling Yuan; Itzhak Kurek; James English; Robert Keenan
Journal:  Microbiol Mol Biol Rev       Date:  2005-09       Impact factor: 11.056

2.  On the evolution of new metabolic functions in diploid organisms.

Authors:  B G Hall
Journal:  Genetics       Date:  1980-12       Impact factor: 4.562

3.  Position of the lacZX90 mutation and hybridization between complete and incomplete beta-galactosidase.

Authors:  W Mandecki; A V Fowler; I Zabin
Journal:  J Bacteriol       Date:  1981-08       Impact factor: 3.490

4.  Properties of beta-galactosidase III: implications for entry of galactosides into Klebsiella.

Authors:  B G Hall
Journal:  J Bacteriol       Date:  1980-05       Impact factor: 3.490
  4 in total

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