| Literature DB >> 45719 |
D M Goldenberg1, R A Pavia, L Smith.
Abstract
A karyological analysis of the G-banded chromosomes of the serially transplantable GW-39 human colonic carcinoma was undertaken. GW-39 cells harvested from hamsters, nude (athymic) mice and cell cultures from 1972 to 1976 revealed a hypodiploid stemline of 45 human chromosomes, with a consistent loss of a 21-chromosome. No apparent alterations of the near-diploid stemline resulted during long-term xenogeneic propagation of this human cancer line.Entities:
Mesh：
Year: 1977 PMID： 45719 DOI： 10.1016/s0304-3835(77)80021-9
Source DB: PubMed Journal: Cancer Lett ISSN： 0304-3835 Impact factor: 8.679