Literature DB >> 4570969

The binding of metyrapone to cytochrome P-450 and its inhibitory action on microsomal hepatic mixed function oxidation reactions.

A G Hildebrandt.   

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Year:  1972        PMID: 4570969

Source DB:  PubMed          Journal:  Biochem Soc Symp        ISSN: 0067-8694


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  10 in total

1.  An improved assay for bacterial methane mono-oxygenase: some properties of the enzyme from Methylomonas methanica.

Authors:  J Colby; H Dalton; R Whittenbury
Journal:  Biochem J       Date:  1975-11       Impact factor: 3.857

2.  Non-competitive and competitive inhibition of mixed function oxidase in rat liver microsomes by metyrapone.

Authors:  I Roots; A G Hildebrandt
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1973       Impact factor: 3.000

3.  Active centers of microsomal cytochrome P-450 determined with metyrapone by mutural depletion system kinetics.

Authors:  I Roots; A G Hildebrandt
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1973       Impact factor: 3.000

4.  Studies on the Specificity and Site of Action of alpha-Cyclopropyl-alpha-[p-methoxyphenyl]-5-pyrimidine Methyl Alcohol (Ancymidol), a Plant Growth Regulator.

Authors:  R C Coolbaugh; S S Hirano; C A West
Journal:  Plant Physiol       Date:  1978-10       Impact factor: 8.340

5.  Short-term kinetics of serum adrenal steroids and plasma ACTH after a single dose of metyrapone in man.

Authors:  M Schöneshöfer; B Schefzig; S Arabin
Journal:  J Endocrinol Invest       Date:  1980 Jul-Sep       Impact factor: 4.256

6.  The effect of chlorpromazine, metyrapone, imipramine and SKF 525-A on the hepatic first pass elimination of propranolol in the pithed rat.

Authors:  H E Barber; N R Kitteringham; J C Petrie
Journal:  Br J Pharmacol       Date:  1982-12       Impact factor: 8.739

7.  5-Hydroxytryptamine is biotransformed by CYP2C9, 2C19 and 2B6 to hydroxylamine, which is converted into nitric oxide.

Authors:  Caroline Fradette; Nobuharu Yamaguchi; Patrick Du Souich
Journal:  Br J Pharmacol       Date:  2004-01-12       Impact factor: 8.739

8.  Mechanisms of action of lipoxygenase and cytochrome P-450-mono-oxygenase inhibitors in blocking endothelium-dependent vasodilatation.

Authors:  U Förstermann; U Alheid; J C Frölich; A Mülsch
Journal:  Br J Pharmacol       Date:  1988-03       Impact factor: 8.739

9.  Metyrapone: an agent for melatonin as well as ACTH and cortisol secretion.

Authors:  K Brismar; S Werner; M Thorén; L Wetterberg
Journal:  J Endocrinol Invest       Date:  1985-04       Impact factor: 4.256

10.  Chromate metabolism in liver microsomes.

Authors:  K W Jennette
Journal:  Biol Trace Elem Res       Date:  1979-03       Impact factor: 3.738

  10 in total

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