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Literature DB >> 4570924

Identification of the block in the intracellular replication of single-stranded DNA of photodynamically inactivated bacteriophage phi X174.

Abstract

(32)P-labeled single-stranded DNA phage phiX174 was photodynamically inactivated by irradiation in air with visible light in the presence of the acridine dye, proflavine sulfate. The inactivated phages could adsorb to the host cells but failed to lyse them. Formation of intracellular mature phages was almost completely inhibited. Photodynamic lesions in phiX174 DNA caused intracellular formation of defective double-stranded replicative form molecules which ultimately reverted to the single-stranded configuration.

Entities: Chemical Species

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Year: 1973 PMID： 4570924 PMCID： PMC355111

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

8 in total

1. THE INTRACELLULAR FATE OF RABBITPOX VIRUS RENDERED NONINFECTIOUS BY VARIOUS REAGENTS.

Authors: W K JOKLIK
Journal: Virology Date: 1964-04 Impact factor: 3.616

2. NUCLEOTIDE COMPOSITION OF SHORT SEGMENTS OF DNA MOLECULES.

Authors: Y MIYAZAWA; C A THOMAS
Journal: J Mol Biol Date: 1965-02 Impact factor: 5.469

3. Studies in partially resolved bacteriophage-host systems. VII. Diamines, dyes, empty phage heads, and protoplast-infecting agent.

Authors: D FRASER; H R MAHLER
Journal: Biochim Biophys Acta Date: 1961-10-14

8. Greater vulnerability of the infecting viral strand of replicative-form deoxyribonucleic acid of bacteriophage phi X174.

Authors: B Datta; R K Poddar
Journal: J Virol Date: 1970-11 Impact factor: 5.103

8 in total

3 in total

1. Ultraviolet reactivation of the single stranded DNA phage phiX 174.

Authors: C K DasGupta; R K Poddar
Journal: Mol Gen Genet Date: 1975-08-05

2. Photodynamic treatment of herpes simplex virus during its replicative cycle.

Authors: N C Khan; J L Melnick; N Biswal
Journal: J Virol Date: 1977-01 Impact factor: 5.103

3. Photodynamic effect of proflavine on phiX174 bacteriophage, its DNA replicative form and its isolated single-stranded DNA: inactivation, mutagenesis and repair.

Authors: J Piette; C M Calberg-Bacq; A Van de Vorst
Journal: Mol Gen Genet Date: 1978-11-16

3 in total

Identification of the block in the intracellular replication of single-stranded DNA of photodynamically inactivated bacteriophage phi X174.

1. THE INTRACELLULAR FATE OF RABBITPOX VIRUS RENDERED NONINFECTIOUS BY VARIOUS REAGENTS.

2. NUCLEOTIDE COMPOSITION OF SHORT SEGMENTS OF DNA MOLECULES.

3. Studies in partially resolved bacteriophage-host systems. VII. Diamines, dyes, empty phage heads, and protoplast-infecting agent.

4. Photodynamic inactivation of free and vegatative bacteriophage T4.

Review 5. Bacteriophage phi-X174 and related viruses.

6. Mechanism of photoinactivation of coliphage T-7 sensitized by acridine orange.

7. Acridine orange-sensitized photoinactivation of T4 bacteriophage. II. Genetic studies with photoinactivated phage.

8. Greater vulnerability of the infecting viral strand of replicative-form deoxyribonucleic acid of bacteriophage phi X174.

1. Ultraviolet reactivation of the single stranded DNA phage phiX 174.

2. Photodynamic treatment of herpes simplex virus during its replicative cycle.

3. Photodynamic effect of proflavine on phiX174 bacteriophage, its DNA replicative form and its isolated single-stranded DNA: inactivation, mutagenesis and repair.