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Literature DB >> 4570252

Nature of hyperacute (accelerated second set) rejection in dog renal allografts and effects of heparin on rejection process.

A H Amery, G D Pegrum, R A Risdon, G Williams.

Abstract

Renal allografts were exchanged between unrelated mongrel dogs after previous sensitization with skin and kidney grafts from the same donors. Rapid rejection of the renal allografts was associated with the accumulation of platelets and leucocytes in the peritubular and glomerular capillaries but fibrin deposition was not demonstrated.Heparin infusion delayed but did not prevent the rejection process.

Entities: Chemical Disease Species

Mesh：

Substances：
Heparin

Year: 1973 PMID： 4570252 PMCID： PMC1588454 DOI： 10.1136/bmj.1.5851.455

Source DB: PubMed Journal: Br Med J ISSN： 0007-1447

14 in total

1. Hyperacute rejection in human-kidney allografts-shwartzman or arthus reaction?

Authors: J A Myburgh; I Cohen; L Gecelter; A M Meyers; C Abrahams; K I Furman; B Goldberg; P J van Blerk
Journal: N Engl J Med Date: 1969-07-17 Impact factor: 91.245

2. In vitro studies on the mechanism of hyperacute xenograft rejection.

Authors: W Land; A Schilling; J Aldenhoff; R Lamerz; K Pielsticker; N Mendler; W Brendel
Journal: Transplant Proc Date: 1971-03 Impact factor: 1.066

3. Relationship between structural and functional changes in rejecting renal xenograft.

Authors: B S Linn; J A Jensen; V Pardo; D Davies; L Franklin
Journal: Transplant Proc Date: 1971-03 Impact factor: 1.066

4. Effect of heparin, arvin, liver perfusion, and heterologous antiplatelet serum on rejection of pig kidney by dog.

Authors: M Slapak; M Greenbaum; W Bardawil; C Saravis; J Joison; W V McDermott
Journal: Transplant Proc Date: 1971-03 Impact factor: 1.066

5. Prolongation of renal xenografts by the simultaneous sequestration of preformed antibody, inhibition of complement, coagulation and antibody synthesis.

Authors: A W Moberg; A R Shons; H Gewurz; M Mozes; J S Najarian
Journal: Transplant Proc Date: 1971-03 Impact factor: 1.066

6. Modification of xenograft response by selective plasmapheresis.

Authors: F K Merkel; M Bier; C D Beavers; W G Merriman; C Wilson; T E Starzl
Journal: Transplant Proc Date: 1971-03 Impact factor: 1.066

7. The nature of experimental second-set kidney transplant rejection. 1. The role of coagulation in hyperacute (second-set) renal allotransplant rejection in dogs.

Authors: G F Pineo; E Regoeczi; W J Dempster
Journal: Br J Exp Pathol Date: 1970-12

Nature of hyperacute (accelerated second set) rejection in dog renal allografts and effects of heparin on rejection process.

1. Hyperacute rejection in human-kidney allografts-shwartzman or arthus reaction?

2. In vitro studies on the mechanism of hyperacute xenograft rejection.

3. Relationship between structural and functional changes in rejecting renal xenograft.

4. Effect of heparin, arvin, liver perfusion, and heterologous antiplatelet serum on rejection of pig kidney by dog.

5. Prolongation of renal xenografts by the simultaneous sequestration of preformed antibody, inhibition of complement, coagulation and antibody synthesis.

6. Modification of xenograft response by selective plasmapheresis.

7. The nature of experimental second-set kidney transplant rejection. 1. The role of coagulation in hyperacute (second-set) renal allotransplant rejection in dogs.

8. Heparin and aspirin in the treatment of hyperacute rejection of renal allografts in presensitized dogs.

9. Relationship of platelets, blood coagulation, and fibrinolysis to hyperacute rejection of renal xenografts.

10. Intravascular coagulation (IVC) in human renal allograft rejection.

1. Organ specificity in hyperacute rejection of canine heart and kidney allografts.