Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 [Methotrexate in the therapy of malaria].

Literature DB >> 4569629

[Methotrexate in the therapy of malaria].

A Wildbolz.

Abstract

Entities: Chemical Disease

Mesh：

Substances：
Hemoglobins
Methotrexate

Year: 1973 PMID： 4569629

Source DB: PubMed Journal: Ther Umsch ISSN： 0040-5930

Keyword Cloud
Cited

× No keyword cloud information.

6 in total

1. A phase I trial to evaluate the safety and pharmacokinetics of low-dose methotrexate as an anti-malarial drug in Kenyan adult healthy volunteers.

Authors: Roma Chilengi; Rashid Juma; Ahmed M Abdallah; Mahfudh Bashraheil; Hudson Lodenyo; Priscilla Nyakundi; Evelyn Anabwani; Amina Salim; Gabriel Mwambingu; Ednah Wenwa; Julie Jemutai; Chemtai Kipkeu; George O Oyoo; Simon N Muchohi; Gilbert Kokwaro; Tim Niehues; Trudie Lang; Alexis Nzila
Journal: Malar J Date: 2011-03-16 Impact factor: 2.979

2. In vitro activity of antifolate and polymorphism in dihydrofolate reductase of Plasmodium falciparum isolates from the Kenyan coast: emergence of parasites with Ile-164-Leu mutation.

Authors: Steven M Kiara; John Okombo; Victor Masseno; Leah Mwai; Isabella Ochola; Steffen Borrmann; Alexis Nzila
Journal: Antimicrob Agents Chemother Date: 2009-06-15 Impact factor: 5.191

[Methotrexate in the therapy of malaria].

1. A phase I trial to evaluate the safety and pharmacokinetics of low-dose methotrexate as an anti-malarial drug in Kenyan adult healthy volunteers.

2. In vitro activity of antifolate and polymorphism in dihydrofolate reductase of Plasmodium falciparum isolates from the Kenyan coast: emergence of parasites with Ile-164-Leu mutation.

3. Anti-malarial effect of semi-synthetic drug amitozyn.

4. SAHAquines, Novel Hybrids Based on SAHA and Primaquine Motifs, as Potential Cytostatic and Antiplasmodial Agents.

5. Anticancer agents against malaria: time to revisit?

6. Effect of folate derivatives on the activity of antifolate drugs used against malaria and cancer.