Literature DB >> 456632

The presence of complement in human cervical mucus and its possible relevance to infertility in women with complement-dependent sperm-immobilizing antibodies.

R J Price, B Boettcher.   

Abstract

Full-complement component lytic activity was measured in human midcycle cervical mucus, using a sensitive 51Cr release hemolytic assay. The level measured was 11.5% of the activity of complement in an equal volume of undiluted human serum. The relevance of this level of complement to complement-dependent sperm-immobilizing antibody activity was studied. After 1 hour's incubation with mucus levels of complement, immobilization of about 50% of spermatozoa occurred and after 3 hours' incubation, immobilization of about 70% of spermatozoa occurred.

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Year:  1979        PMID： 456632     DOI： 10.1016/s0015-0282(16)44117-8

Source DB:  PubMed          Journal:  Fertil Steril        ISSN： 0015-0282            Impact factor:   7.329


  35 in total

1.  Enhanced factor H binding to sialylated Gonococci is restricted to the sialylated lacto-N-neotetraose lipooligosaccharide species: implications for serum resistance and evidence for a bifunctional lipooligosaccharide sialyltransferase in Gonococci.

Authors:  Sunita Gulati; Andrew Cox; Lisa A Lewis; Frank St Michael; Jianjun Li; Ryan Boden; Sanjay Ram; Peter A Rice
Journal:  Infect Immun       Date:  2005-11       Impact factor: 3.441

2.  Structure-function studies of the Neisseria gonorrhoeae major outer membrane porin.

Authors:  Adrienne Chen; H Steven Seifert
Journal:  Infect Immun       Date:  2013-09-16       Impact factor: 3.441

3.  Properdin is critical for antibody-dependent bactericidal activity against Neisseria gonorrhoeae that recruit C4b-binding protein.

Authors:  Sunita Gulati; Sarika Agarwal; Shreekant Vasudhev; Peter A Rice; Sanjay Ram
Journal:  J Immunol       Date:  2012-02-24       Impact factor: 5.422

Review 4.  Humoral immune response to gonococcal infections.

Authors:  G F Brooks; C J Lammel
Journal:  Clin Microbiol Rev       Date:  1989-04       Impact factor: 26.132

5.  Characterization of glycosylphosphatidylinositol-anchored decay accelerating factor (GPI-DAF) and transmembrane DAF gene expression in wild-type and GPI-DAF gene knockout mice using polyclonal and monoclonal antibodies with dual or single specificity.

Authors:  T Miwa; X Sun; R Ohta; N Okada; C L Harris; B P Morgan; W C Song
Journal:  Immunology       Date:  2001-10       Impact factor: 7.397

Review 6.  The molecular mechanisms used by Neisseria gonorrhoeae to initiate infection differ between men and women.

Authors:  Jennifer L Edwards; Michael A Apicella
Journal:  Clin Microbiol Rev       Date:  2004-10       Impact factor: 26.132

Review 7.  The mucosal immune system of fish: the evolution of tolerating commensals while fighting pathogens.

Authors:  Daniela Gomez; J Oriol Sunyer; Irene Salinas
Journal:  Fish Shellfish Immunol       Date:  2013-10-05       Impact factor: 4.581

8.  The role of mucus in antibody-mediated rapid expulsion of Trichinella spiralis in suckling rats.

Authors:  M S Carlisle; D D McGregor; J A Appleton
Journal:  Immunology       Date:  1990-05       Impact factor: 7.397

9.  The role of complement component C3b and its receptors in sperm-oocyte interaction.

Authors:  D J Anderson; A F Abbott; R M Jack
Journal:  Proc Natl Acad Sci U S A       Date:  1993-11-01       Impact factor: 11.205

10.  Reproductive immunology in viviparous mammals: evolutionary paradox of interactions among immune mechanisms and autologous or allogeneic gametes and semiallogeneic foetuses.

Authors:  M Samardžija; M Lojkić; N Maćešić; H Valpotić; I Butković; J Šavorić; I Žura Žaja; D Leiner; D Đuričić; F Marković; P Kočila; Z Vidas; M Gerenčer; A Kaštelan; A Milovanović; M Lazarević; D Rukavina; I Valpotić
Journal:  Vet Q       Date:  2020-12       Impact factor: 3.320
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