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Literature DB >> 4564404

Cytoplasmic antigens from Nocardia elicting a specific delayed hypersensitivity.

L Ortiz-Ortiz, M F Contreras, L F Bujalil.

Abstract

Purified cytoplasmic extracts from Nocardia asteroides and N. brasiliensis elicit delayed hypersensitivity in Nocardia-sensitized guinea pigs. The differences in skin reactivity clearly show that it is possible to distinguish between different Nocardia species. When peritoneal exudate cells from the latter animals were obtained and treated with the purified cytoplasmic extracts, their migration was inhibited to a significant degree only by means of the homologous antigen. A mild delayed reactivity was observed when the cytoplasmic antigens were used as skin test materials on animals sensitized with BCG. On the other hand, no inhibition of migration was observed when peritoneal exudate cells from BCG-sensitized guinea pigs were exposed to the cytoplasmic antigens.

Entities: Disease Species

Mesh：

Substances：

Year: 1972 PMID： 4564404 PMCID： PMC422456 DOI： 10.1128/iai.5.6.879-882.1972

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

4 in total

1. Specificity of mycobacterial sensitins. I. Studies in guinea pigs with purified "tuberculin" prepared from mammalian and avian tubercle bacilli, Mycobacterium balnei, and other acid-fast bacilli.

Authors: M MAGNUSSON
Journal: Am Rev Respir Dis Date: 1961-01

2. Purified protoplasmic peptides of mycobacteria: isolation of species-specific peptides from protoplasm of mycobacteria.

Authors: R E Beam; K D Stottmeier; G P Kubica
Journal: J Bacteriol Date: 1969-10 Impact factor: 3.490

3. Delayed hypersensitivity to ribosomal protein from BCG.

Authors: L Ortiz-Ortiz; E B Solarolo; L F Bojalil
Journal: J Immunol Date: 1971-10 Impact factor: 5.422

4. Purified protoplasmic peptides of mycobacteria: in vivo and in vitro comparison of the species specificity of purified protoplasmic peptides and purified protein derivatives of mycobacterial culture filtrates.

Authors: K D Stottmeier; R E Beam; G P Kubica
Journal: J Bacteriol Date: 1969-10 Impact factor: 3.490

4 in total

7 in total

Cytoplasmic antigens from Nocardia elicting a specific delayed hypersensitivity.

1. Specificity of mycobacterial sensitins. I. Studies in guinea pigs with purified "tuberculin" prepared from mammalian and avian tubercle bacilli, Mycobacterium balnei, and other acid-fast bacilli.

2. Purified protoplasmic peptides of mycobacteria: isolation of species-specific peptides from protoplasm of mycobacteria.

3. Delayed hypersensitivity to ribosomal protein from BCG.

4. Purified protoplasmic peptides of mycobacteria: in vivo and in vitro comparison of the species specificity of purified protoplasmic peptides and purified protein derivatives of mycobacterial culture filtrates.

1. Isolation and purification of two immunodominant antigens from Nocardia brasiliensis.

2. B-lymphocyte activation with an extract of Nocardia brasiliensis.

3. In vitro response of rabbit alveolar macrophages to infection with Nocardia asteroides.

4. Immunoglobulin and complement in tissues of mice infected with Nocardia brasiliensis.

5. Effect of cyclophosphamide on experimental Nocardia asteroides infection in mice.

6. Immune response to Nocardia brasiliensis extracellular antigens in patients with mycetoma.

7. Resistance to Nocardia brasiliensis infection in mice immunized with either Nocardia or BCG.