Literature DB >> 4562283

Liver preservation by single passage hypothermic "squirt" perfusion.

R Y Calne, D C Dunn, B M Herbertson, E M Gordon, H Bitter-Suermann, A J Robson, A S Macdonald, D R Davis, D P Smith, F H Reitter, L M Webster.   

Abstract

A single passage, hypothermic, intermittent squirt perfusion of the pig's liver is described which has allowed preservation of porcine livers for up to 17 hours. After preservation, orthotopically allografted livers can maintain recipient animals in good health. If this technique can be applied to clinical liver transplantation it should be possible to move livers from one hospital to another in the same way that kidneys are transported. This should increase the availability of donor livers for transplantation and avoid the serious disadvantages of moving the sick recipient just before the operation to the hospital where the donor has died.

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Year:  1972        PMID: 4562283      PMCID: PMC1786401          DOI: 10.1136/bmj.4.5833.142

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  8 in total

1.  Trickle perfusion for organ preservation.

Authors:  R Y Calne; D C Dunn; R Gajo-Reyero; E J Hadjiyannakis; A J Robson
Journal:  Nature       Date:  1972-01-21       Impact factor: 49.962

2.  24-hour and 72-hour preservation of canine kidneys.

Authors:  F O Belzer; B S Ashby; J E Dunphy
Journal:  Lancet       Date:  1967-09-09       Impact factor: 79.321

3.  Kidney preservation for transportation. Initial perfusion and 30 hours' ice storage.

Authors:  G M Collins; M Bravo-Shugarman; P I Terasaki
Journal:  Lancet       Date:  1969-12-06       Impact factor: 79.321

4.  Successful 20-hour storage of the canine liver by continuous hypothermic perfusion.

Authors:  M D Turner; F Alican
Journal:  Cryobiology       Date:  1970 Jan-Feb       Impact factor: 2.487

5.  Preservation of canine kidneys by hypothermia and low flow perfusion with bloodless perfusate.

Authors:  T J Herrmann; J G Turcotte
Journal:  Arch Surg       Date:  1969-01

6.  A technique of orthotopic liver translantation in the pig.

Authors:  R Y Calne; D E Yoffa; H J White; R R Maginn
Journal:  Br J Surg       Date:  1968-03       Impact factor: 6.939

7.  Successful preservation of pig's liver for 5-8 hours by simple ice storage.

Authors:  E J Hadjiyannakis; R Y Calne; V C Marshall; D R Davis
Journal:  Br J Surg       Date:  1971-11       Impact factor: 6.939

8.  Liver transplantation in man. I. Observations on technique and organization in five cases.

Authors:  R Y Calne; R Williams
Journal:  Br Med J       Date:  1968-11-30
  8 in total
  3 in total

1.  Factors determining successful liver preservation for transplantation.

Authors:  L H Toledo-Pereyra; R L Simmons; J S Najarian
Journal:  Ann Surg       Date:  1975-03       Impact factor: 12.969

2.  Twenty-four- and 48-hour canine liver preservation by simple hypothermia with prostacyclin.

Authors:  M Monden; J G Fortner
Journal:  Ann Surg       Date:  1982-07       Impact factor: 12.969

3.  Canine and human liver preservation for 6 to 18 hr by cold infusion.

Authors:  J Benichou; C G Halgrimson; R Weil; L J Koep; T E Starzl
Journal:  Transplantation       Date:  1977-12       Impact factor: 4.939

  3 in total

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