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Literature DB >> 4557305

Cell-mediated immune reactivity in liver disease.

Abstract

Cell-mediated immunity has been investigated using the leucocyte migration test in 32 patients with chronic active hepatitis or primary biliary cirrhosis. Twenty-six (75%) showed reactivity to liver extract. At least two antigens are involved. Cell-mediated reactivity was confirmed in some cases using lymphocyte ;blast' transformation. There was no correlation with the presence of auto-antibodies.Cell-mediated immunity to parotid extract was shown in 10 cases (28%). This is in accord with the occurrence of the sicca syndrome in liver disease, which has been confirmed in this study.

Entities: Disease Species

Mesh：

Substances：
Antigens
Tissue Extracts

Year: 1972 PMID： 4557305 PMCID： PMC1412206 DOI： 10.1136/gut.13.6.427

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

12 in total

1. Frusemide in acute pulmonary oedema.

Authors: R W Biagi; B N Bapat
Journal: Lancet Date: 1967-04-15 Impact factor: 79.321

2. Lymphocyte stimulation and chronic liver disease.

Authors: H Tobias; A P Safran; F Schaffner
Journal: Lancet Date: 1967-01-28 Impact factor: 79.321

3. Liver disease in Sjögren's syndrome and rheumatoid arthritis.

Authors: K Whaley; R B Goudie; J Williamson; G Nuki; W C Dick; W W Buchanan
Journal: Lancet Date: 1970-04-25 Impact factor: 79.321

4. Impaired delayed hypersensitivity in primary biliary cirrhosis.

Authors: S Sherlock; R A Fox; D G James; P J Scheuer; O Sharma
Journal: Lancet Date: 1969-05-10 Impact factor: 79.321

Review 5. A leucocyte migration technique for in vitro detection of cellular (delayed type) hypersensitivity in man.

Authors: G Bendixen; M Soborg
Journal: Dan Med Bull Date: 1969-01

Review 6. The concept of an 'autoallergic' hepatitis.

Authors: D Doniach
Journal: Proc R Soc Med Date: 1970-05

7. Cellular hypersensitivity in Sjögren's syndrome.

Authors: M Soborg; U Bertram
Journal: Acta Med Scand Date: 1968-10

8. Immune processes in the pathogenesis of liver disease.

Authors: H Popper; F Paronetto; F Schaffner
Journal: Ann N Y Acad Sci Date: 1965-06-30 Impact factor: 5.691

9. Impaired Lymphocyte Transformation and Delayed Hypersensitivity in Sjögren's Syndrome.

Authors: B G Leventhal; D S Waldorf; N Talal
Journal: J Clin Invest Date: 1967-08 Impact factor: 14.808

10. "Sicca complex" in liver disease.

Authors: P L Golding; R Bown; A M Mason; E Taylor
Journal: Br Med J Date: 1970-11-07

12 in total

1. T and B lymphocytes in patients with chronic active hepatitis (CAH).

Authors: M Colombo; S J Vernace; F Paronetto
Journal: Clin Exp Immunol Date: 1977-10 Impact factor: 4.330

2. In vitro morphological studies on antibody-dependent nonimmune lymphocyte-mediated cytotoxicity in chronic active liver disease.

Authors: H Kawanishi
Journal: Am J Dig Dis Date: 1978-02

Review 3. The immunology of liver disorders.

Authors: G Walker
Journal: Proc R Soc Med Date: 1974-06

4. [Cellular immune reactions towards homologous liver-specific antigens (HLP) in chronic inflammatory liver diseases (author's transl)].

Authors: K H von Meyer zum Büschenfelde; J Knolle; J Berger
Journal: Klin Wochenschr Date: 1974-03-01