| Literature DB >> 45558 |
R M Fox1.
Abstract
The use of high dose methotrexate therapy in the treatment of malignant disease has been complicated by nephrotoxicity. Analysis of the basic physico-chemical properties of methotrexate has allowed the development of improved techniques of administering methotrexate, at high dose, which greatly reduces the incidence of nephrotoxicity.Entities:
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Year: 1979 PMID: 45558
Source DB: PubMed Journal: Clin Exp Pharmacol Physiol Suppl ISSN: 0143-9294