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Literature DB >> 4553943

Insulin infusion test of gastric acid secretion.

D C Carter, R R Dozois, J R Kirkpatrick.

Abstract

In view of the disadvantages of the standard insulin test for completeness of vagotomy a continuous insulin infusion test has been developed. Twenty-six tests were carried out on 12 healthy male volunteers. A dose of 0.04 unit of soluble insulin/kg/hr was found to produce the highest acid secretion with the least severity of symptoms of hypoglycaemia. The pattern of response was a plateau of acid secretion and of hypoglycaemia, and repeated studies in six subjects showed that the results were reproducible. Evaluation of this test after vagotomy and comparison with the standard insulin test are now required.

Entities: Gene

Mesh：

Substances：
Blood Glucose
Insulin

Year: 1972 PMID： 4553943 PMCID： PMC1787941 DOI： 10.1136/bmj.2.5807.202

Source DB: PubMed Journal: Br Med J ISSN： 0007-1447

4 in total

Insulin infusion test of gastric acid secretion.

1. The long term stability of the insulin test.

2. Cardiovascular effects of induced insulin hypoglycemia in man during the Hollander test.

3. Positioning of subject and of nasogastric tube during a gastric secretion study.

4. Histamine- and insulin-stimulated gastric acid secretion after selective and truncal vagotomy.

1. Letters to the editor: Postvagotomy insulin infusion test.

2. The response of gastric secretion and serum gastrin to an insulin infusion test in patients with duodenal ulcer.

3. Effect of partial and total vagotomy on the gastric acid response to an insulin infusion in the dog.

4. The gastric secretory response to a continuous insulin infusion in the dog.