Literature DB >> 4553818

Tranexamic acid in control of haemorrhage after dental extraction in haemophilia and Christmas disease.

C D Forbes, R D Barr, G Reid, C Thomson, C R Prentice, G P McNicol, A S Douglas.   

Abstract

In a double-blind trial tranexamic acid (AMCA, Cyclokapron), 1 g three times a day for five days, significantly reduced blood loss and transfusion requirements after dental extraction in patients with haemophilia and Christmas disease. No side effects were seen in either group of patients. Screening tests showed no toxic action of tranexamic acid on the liver, kidney, or heart.

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Year:  1972        PMID： 4553818      PMCID： PMC1788188          DOI： 10.1136/bmj.2.5809.311

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  17 in total

1.  The kaolin clotting time; a rapid one-stage method for diagnosis of coagulation defects.

Authors:  J MARGOLIS
Journal:  J Clin Pathol       Date:  1958-09       Impact factor: 3.411

2.  Epsilon-Aminocaproic acid therapy for dental extractions in haemophilia and Christmas disease: a double blind controlled trial.

Authors:  P N Walsh; C R Rizza; J M Matthews; J Eipe; P B Kernoff; M D Coles; A L Bloom; B M Kaufman; P Beck; C M Hanan; R Biggs
Journal:  Br J Haematol       Date:  1971-05       Impact factor: 6.998

3.  High obstruction of urine flow as a complication of the treatment with fibrinolysis inhibitors of haematuria in haemophiliacs.

Authors:  H van Itterbeek; J Vermylen; M Verstraete
Journal:  Acta Haematol       Date:  1968-04       Impact factor: 2.195

4.  Comparative studies on inhibitors of fibrinolysis in vitro and in vivo.

Authors:  E Deutsch; M Fischer
Journal:  Acta Haematol       Date:  1968       Impact factor: 2.195

5.  [Therapy of post-extraction hemorrhages in hemophiliac patients with epsilon-aminocaproic acid (EACA)].

Authors:  M P Marini; F Arturi; G Crolle
Journal:  Haematologica       Date:  1966       Impact factor: 9.941

6.  Dental extractions in hemopholic patients on aminocaproic acid prophylaxis. Report of three cases.

Authors:  N D Giordano; R S Watkins; M Radivogevitch; E Goodsitt
Journal:  Oral Surg Oral Med Oral Pathol       Date:  1967-08

7.  Epsilon-aminocaproic acid therapy for dental extractions in haemophiliacs.

Authors:  M W Cooksey; C B Perry; A B Raper
Journal:  Br Med J       Date:  1966-12-31

8.  Epsilon-aminocaproic acid in the treatment of haemophilia and Christmas disease with special reference to the extraction of teeth.

Authors:  R W Tavenner
Journal:  Br Dent J       Date:  1968-01-02       Impact factor: 1.626

9.  The use of epsilon aminocaproic acid as supplementary treatment of the haemophiliac undergoing surgery.

Authors:  A J Paddon
Journal:  J Dent Assoc S Afr       Date:  1967-03-15

10.  [Utilization of epsilon-amino-caproic acid in hemostasis in stomatology in hemophiliacs].

Authors:  D Alagille; A Lambert; P Laudenbach; M Poulain
Journal:  Revue Stomatol       Date:  1965 Apr-May
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  24 in total

1.  Tranexamic acid modulates the immune response and reduces postsurgical infection rates.

Authors:  Dominik F Draxler; Kah Yep; Gryselda Hanafi; Anoushka Winton; Maria Daglas; Heidi Ho; Maithili Sashindranath; Lisa M Wutzlhofer; Andrew Forbes; Isaac Goncalves; Huyen A Tran; Sophia Wallace; Magdalena Plebanski; Paul S Myles; Robert L Medcalf
Journal:  Blood Adv       Date:  2019-05-28

Review 2.  Basis of antifibrinolytic therapy.

Authors:  C R Prentice
Journal:  J Clin Pathol Suppl (R Coll Pathol)       Date:  1980

Review 3.  Inhibitors of fibrinolysis in the treatment of haemophilia.

Authors:  C R Rizza
Journal:  J Clin Pathol Suppl (R Coll Pathol)       Date:  1980

4.  Antifibrinolytic therapy in genitourinary tract surgery.

Authors:  L Andersson
Journal:  J Clin Pathol Suppl (R Coll Pathol)       Date:  1980

5.  ASH ISTH NHF WFH 2021 guidelines on the management of von Willebrand disease.

Authors:  Nathan T Connell; Veronica H Flood; Romina Brignardello-Petersen; Rezan Abdul-Kadir; Alice Arapshian; Susie Couper; Jean M Grow; Peter Kouides; Michael Laffan; Michelle Lavin; Frank W G Leebeek; Sarah H O'Brien; Margareth C Ozelo; Alberto Tosetto; Angela C Weyand; Paula D James; Mohamad A Kalot; Nedaa Husainat; Reem A Mustafa
Journal:  Blood Adv       Date:  2021-01-12

Review 6.  Preventing perioperative bleeding in patients with inherited bleeding disorders.

Authors:  Colin Watterson; Nicholas Beacher
Journal:  Evid Based Dent       Date:  2017-03

Review 7.  The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients.

Authors:  Johnny Cai; Jessica Ribkoff; Sven Olson; Vikram Raghunathan; Hanny Al-Samkari; Thomas G DeLoughery; Joseph J Shatzel
Journal:  Eur J Haematol       Date:  2019-12-16       Impact factor: 2.997

Review 8.  Clinical application of inhibitors of fibrinolysis.

Authors:  M Verstraete
Journal:  Drugs       Date:  1985-03       Impact factor: 9.546

9.  Abrogating fibrinolysis does not improve bleeding or rFVIIa/rFVIII treatment in a non-mucosal venous injury model in haemophilic rodents.

Authors:  R Stagaard; M J Flick; B Bojko; K Goryński; P Z Goryńska; C D Ley; L H Olsen; T Knudsen
Journal:  J Thromb Haemost       Date:  2018-06-21       Impact factor: 5.824

10.  End Stage Renal Disease: Not a Contraindication for Minor Oral Surgery-Protocol for the Management of Oral Surgery patients with ESRD on Hemodialysis.

Authors:  Sneha Pendem; G Lakshmi Narayana; Poornima Ravi
Journal:  J Maxillofac Oral Surg       Date:  2016-07-28
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