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Literature DB >> 4552992

Studies on Escherichia coli enzymes involved in the synthesis of uridine diphosphate-N-acetyl-muramyl-pentapeptide.

Abstract

The specific activities of l-alanine:d-alanine racemase, d-alanine:d-alanine ligase, and the l-alanine, d-glutamic acid, meso-diaminopimelic acid, and d-alanyl-d-alanine adding enzymes were followed during growth of Escherichia coli. The specific activities were nearly independent of the growth phase. d-Alanine:d-alanine ligase was inhibited by d-alanyl-d-alanine, d-cycloserine, glycine, and glycyl-glycine. l-Alanine:d-alanine racemase was found to be sensitive to d-cycloserine, glycine, and glycyl-glycine. The l-alanine adding enzyme was inhibited by glycine and glycyl-glycine.

Entities: Chemical Gene Species

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Year: 1972 PMID： 4552992 PMCID： PMC247374 DOI： 10.1128/jb.110.1.26-34.1972

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

16 in total

1. Biosynthesis of the peptidoglycan of bacterial cell walls. 8. Peptidoglycan transpeptidase and D-alanine carboxypeptidase: penicillin-sensitive enzymatic reaction in strains of Escherichia coli.

Authors: K Izaki; M Matsuhashi; J L Strominger
Journal: J Biol Chem Date: 1968-06-10 Impact factor: 5.157

2. D-amino acids as inducers of L-alanine dehydrogenase in Bacillus subtilis.

Authors: R Berberich; M Kaback; E Freese
Journal: J Biol Chem Date: 1968-03-10 Impact factor: 5.157

3. Peptidoglycan transpeptidase and D-alanine carboxypeptidase: penicillin-sensitive enzymatic reactions.

Authors: J L Strominger; K Izaki; M Matsuhashi; D J Tipper
Journal: Fed Proc Date: 1967 Jan-Feb

4. Coenzyme content of purified alanine racemase from Pseudomonas.

Authors: G Rosso; K Takashima; E Adams
Journal: Biochem Biophys Res Commun Date: 1969-01-06 Impact factor: 3.575

5. Reversal of the growth inhibitory action of glycine and glycylglycine by alanylalanine in Mycobacterium smegmatis.

Authors: K Yabu
Journal: Biochim Biophys Acta Date: 1969-07-30

6. Selective inhibition of enzymes utilizing alanine in the biosynthesis of peptidoglycan.

Authors: F C Neuhaus
Journal: Antimicrob Agents Chemother (Bethesda) Date: 1967

7. A simple method for following the fate of alanine-containing components in murein synthesis in Escherichia coli.

Authors: E J Lugtenberg; P G de Haan
Journal: Antonie Van Leeuwenhoek Date: 1971 Impact factor: 2.271

8. Murein synthesis and identification of cell wall precursors of temperature-sensitive lysis mutants of Escherichia coli.

Authors: E J Lugtenberg; L De Haas-Menger; W H Ruyters
Journal: J Bacteriol Date: 1972-01 Impact factor: 3.490

9. In vivo and in vitro action of new antibiotics interfering with the utilization of N-acetyl-glucosamine-N-acetyl-muramyl-pentapeptide.

Authors: E J Lugtenberg; A v Schijndel-van Dam; T H van Bellegem
Journal: J Bacteriol Date: 1971-10 Impact factor: 3.490

10. Effects of penicillin and glycine on cell wall glycopeptides of the two varieties of Vibrio fetus.

Authors: P H Fung; A J Winter
Journal: J Bacteriol Date: 1968-12 Impact factor: 3.490

21 in total

1. Bacterial and fungal growth in total parenteral nutrition solutions,.

Authors: M L Failla; C D Benedict; E D Weinberg
Journal: Antonie Van Leeuwenhoek Date: 1975 Impact factor: 2.271

2. The VANA glycopeptide resistance protein is related to D-alanyl-D-alanine ligase cell wall biosynthesis enzymes.

Authors: S Dutka-Malen; C Molinas; M Arthur; P Courvalin
Journal: Mol Gen Genet Date: 1990-12

3. Temperature-sensitive murein synthesis in an Escherichia coli pdx mutant and the role of alanine racemase.

Authors: D W Grogan
Journal: Arch Microbiol Date: 1988 Impact factor: 2.552

4. Pleiotropic mutations in Escherichia coli conferring tolerance to glycine and sensitivity to penicillin.

Authors: H J Wijsman; H C Pafort
Journal: Mol Gen Genet Date: 1974

5. Temperature-sensitive mutants of Escherichia coli K-12 with low activities of the L-alanine adding enzyme and the D-alanyl-D-alanine adding enzyme.

Authors: E J Lugtenberg; A v Schijndel-van Dam
Journal: J Bacteriol Date: 1972-04 Impact factor: 3.490

6. Temperature-sensitive mutants of Escherichia coli K-12 with low activity of the diaminopimelic acid adding enzyme.