Literature DB >> 4551977

A factor that can be used to regulate an in vitro primary immune response.

J Watson, M Thoman.   

Abstract

A factor has been isolated that supports the stimulation of an immune response against heterologous erythrocyte antigens in mouse spleen cells cultured in a medium that contains deficient serum. The factor is secreted by certain spleen cells that are obtained in permanent culture after leukemia virus infection. The factor permits antigen-sensitive cells derived from bone marrow to mature to antibody-forming cells. This factor can be used in controlling the initiation of a primary immune response in vitro.

Entities:  

Mesh：

Substances：

Year:  1972        PMID： 4551977      PMCID： PMC426514          DOI： 10.1073/pnas.69.3.594

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  19 in total

1.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

2.  Long-term propagation of the Rauscher murine leukemia virus in tissue culture.

Authors:  B S Wright; J C Lasfargues
Journal:  J Natl Cancer Inst       Date:  1965-08       Impact factor: 13.506

3.  The third cell type required for the immune response of spleen cells in vitro.

Authors:  H Cosenza; L D Leserman; D A Rowley
Journal:  J Immunol       Date:  1971-08       Impact factor: 5.422

4.  The structure and assembly of murine leukemia virus: intracellular viral RNA.

Authors:  J D Watson
Journal:  Virology       Date:  1971-09       Impact factor: 3.616

5.  Immune response restoration with macrophage culture supernatants.

Authors:  M Hoffmann; R W Dutton
Journal:  Science       Date:  1971-06-04       Impact factor: 47.728

6.  Immunocompetence of transferred thymus-marrow cell combinations.

Authors:  H N Claman; E A Chaperon; R F Triplett
Journal:  J Immunol       Date:  1966-12       Impact factor: 5.422

7.  Hemoglobin synthesis in murine virus-induced leukemic cells in vitro: stimulation of erythroid differentiation by dimethyl sulfoxide.

Authors:  C Friend; W Scher; J G Holland; T Sato
Journal:  Proc Natl Acad Sci U S A       Date:  1971-02       Impact factor: 11.205

8.  Cell components in the immune response. I. Gradient separation of immune cells.

Authors:  R I Mishell; R W Dutton; D J Raidt
Journal:  Cell Immunol       Date:  1970-07       Impact factor: 4.868

9.  Cell components in the immune response. II. Cell attachment separation of immune cells.

Authors:  K Hartmann; R W Dutton; M M McCarthy; R I Mishell
Journal:  Cell Immunol       Date:  1970-07       Impact factor: 4.868

10.  Immunization of dissociated spleen cell cultures from normal mice.

Authors:  R I Mishell; R W Dutton
Journal:  J Exp Med       Date:  1967-09-01       Impact factor: 14.307
View more
  3 in total

1.  Suppression of in vitro antibody response by spleen cells of mice infected with Friend-associated lymphatic leukemia virus.

Authors:  M Bendinelli; D Matteucci; A Toniolo; H Friedman
Journal:  Infect Immun       Date:  1979-04       Impact factor: 3.441

2.  Immunoglobulin synthesis in vitro by lymphocytes from patients with immune deficiency: requirements for a special serum factor.

Authors:  P Wernet; F P Siegal; H Dickler; S Fu; H G Kunkel
Journal:  Proc Natl Acad Sci U S A       Date:  1974-02       Impact factor: 11.205

3.  The use of bacterial lipopolysaccharides to show that two signals are required for the induction of antibody synthesis.

Authors:  J Watson; E Trenkner; M Cohn
Journal:  J Exp Med       Date:  1973-09-01       Impact factor: 14.307
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.