Literature DB >> 4549739

1alpha-Hydroxyvitamin D2: a potent synthetic analog of vitamin D2.

H Y Lam, H K Schnoes, H F DeLuca.   

Abstract

A hydroxy analog of vitamin D(2), 1alpha-hydroxyvitamin D(2), has been synthesized and tested for biological activity. This vitamin derivative is active in stimulating intestinal calcium transport and bone calcium mobilization in the rat and exhibits antirachitic activity. Its biopotency is comparable to that of the corresponding vitamin D(3) analog, 1alpha-hydroxyvitamin D(3).

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Year:  1974        PMID： 4549739     DOI： 10.1126/science.186.4168.1038

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  4 in total

1.  Direct C-1 hydroxylation of vitamin D compounds: convenient preparation of 1alpha-hydroxyvitamin D3, 1alpha, 25-dihydroxyvitamin D3, and 1alpha-hydroxyvitamin D2.

Authors:  H E Paaren; D E Hamer; H K Schnoes; H F DeLuca
Journal:  Proc Natl Acad Sci U S A       Date:  1978-05       Impact factor: 11.205

2.  1 alpha,24(S)-dihydroxyvitamin D2: a biologically active product of 1 alpha-hydroxyvitamin D2 made in the human hepatoma, Hep3B.

Authors:  S Strugnell; V Byford; H L Makin; R M Moriarty; R Gilardi; L W LeVan; J C Knutson; C W Bishop; G Jones
Journal:  Biochem J       Date:  1995-08-15       Impact factor: 3.857

3.  1 alpha-Hydroxyvitamin D2 inhibits growth of human neuroblastoma.

Authors:  Paul R van Ginkel; William Yang; Marcus M Marcet; Clement C Chow; Amol D Kulkarni; Soesiawati Darjatmoko; Mary J Lindstrom; Janice Lokken; Saswati Bhattacharya; Daniel M Albert
Journal:  J Neurooncol       Date:  2007-06-30       Impact factor: 4.130

Review 4.  100 YEARS OF VITAMIN D: Historical aspects of vitamin D.

Authors:  Glenville Jones
Journal:  Endocr Connect       Date:  2022-04-22       Impact factor: 3.221
  4 in total

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