Literature DB >> 4547742

Effect of development and aging on the response of canine lymphocytes to phytohemagglutinin.

J D Gerber, A L Brown.   

Abstract

The stage of development and age were found to effect the responsiveness of dog T-lymphocytes to phytohemagglutinin. T-lymphocytes from beagles 0 to 4 weeks of age showed significantly less response to phytohemagglutinin (P < 0.001) than T-lymphocytes from these same dogs at 6 to 12 weeks of age. Peak response to phytohemagglutinin occurred between 6 weeks to 6 months of age, after which there was a significant correlation (P < 0.02) between increase in age and decrease in phytohemagglutinin responsiveness.

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Year:  1974        PMID: 4547742      PMCID: PMC423008          DOI: 10.1128/iai.10.4.695-699.1974

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  44 in total

1.  A nomograph that predicts the age to vaccinate puppies against distemper.

Authors:  J A BAKER; D S ROBSON; J H GILLESPIE; J A BURGHER; M F DOUGHTY
Journal:  Cornell Vet       Date:  1959-01

2.  The cholinesterase activity of the serum on newborn animals, and of colostrum.

Authors:  R A McCANCE; A O HUTCHINSON
Journal:  Biochem J       Date:  1949       Impact factor: 3.857

3.  Mitogenic effect of phytohaemagglutinin at different ages.

Authors:  A V Pisciotta; D W Westring; C DePrey; B Walsh
Journal:  Nature       Date:  1967-07-08       Impact factor: 49.962

4.  Cell-mediated immune response in the developing dog.

Authors:  B J Bryant; M Shifrine; C McNeil
Journal:  Int Arch Allergy Appl Immunol       Date:  1973

5.  Measles as an index of immunological function.

Authors:  F M Burnet
Journal:  Lancet       Date:  1968-09-14       Impact factor: 79.321

6.  An in-vitro quantitative study of phytohaemagglutinin (PHA) induced transformation of lymphocytes from premature newborn infants, from older premature infants, and from full-term newborn infants.

Authors:  G Prindull
Journal:  Blut       Date:  1971-07

7.  Decreased lymphoid cell multiplication in the post-thymectomy state.

Authors:  H J Meuwissen; P A Van Alten; R A Good
Journal:  Transplantation       Date:  1969-01       Impact factor: 4.939

8.  Development of immunity in fetal dogs: humoral responses.

Authors:  R O Jacoby; R A Dennis; R A Griesemer
Journal:  Am J Vet Res       Date:  1969-09       Impact factor: 1.156

9.  Lymphocyte activation. I. Response of T and B lymphocytes to phytomitogens.

Authors:  G Janossy; M F Greaves
Journal:  Clin Exp Immunol       Date:  1971-10       Impact factor: 4.330

10.  Relationship between measles and canine distemper viruses determined by delayed type hypersensitivity reactions in dogs.

Authors:  A L Brown; R E McCarthy
Journal:  Nature       Date:  1974-03-22       Impact factor: 49.962

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  5 in total

1.  Ageing and immunity in outbred NMRI mice: lack of correlation between age-related decline of the response to T cell mitogens, the antibody response to a T-dependent antigen and lifespan in outbred NMRI mice.

Authors:  F Joncourt; F Kristensen; A L De Weck
Journal:  Clin Exp Immunol       Date:  1981-05       Impact factor: 4.330

2.  Lymphocyte response to T-cell mitogen during experimental gingivitis in humans.

Authors:  N P Lang; F N Smith
Journal:  Infect Immun       Date:  1976-01       Impact factor: 3.441

3.  Immune responses of dairy cattle to parainfluenza-3 virus in intranasal infectious bovine rhinotracheitis-parainfluenza-3 virus vaccines.

Authors:  A L Burroughs; J L Morrill; J L Bostwick; R K Ridley; H C Fryer
Journal:  Can J Comp Med       Date:  1982-07

Review 4.  Development of Dog Immune System: From in Uterus to Elderly.

Authors:  Maria Pereira; Ana Valério-Bolas; Cátia Saraiva-Marques; Graça Alexandre-Pires; Isabel Pereira da Fonseca; Gabriela Santos-Gomes
Journal:  Vet Sci       Date:  2019-10-21

5.  Possible association of thymus dysfunction with fading syndromes in puppies and kittens.

Authors:  J A Roth
Journal:  Vet Clin North Am Small Anim Pract       Date:  1987-05       Impact factor: 2.093

  5 in total

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