Literature DB >> 4546946

The effect of age on the fibrinolytic enzyme system.

P J Hamilton, A A Dawson, D Ogston, A S Douglas.   

Abstract

Components of the fibrinolytic enzyme system, FR-antigen and fibrinogen, were measured in 20 healthy volunteers aged 20-40 years and in 61 elderly subjects aged 66-96 years. Plasminogen activator levels did not significantly differ between the 20-40 and 66-75 age groups, but were higher in those over 75. Plasminogen showed no change with age except for a fall in those over 75. Fibrinogen, FR-antigen, alpha(1)-antitrypsin, and alpha(2)-macroglobulin all rose with age, but the mean fibrinogen concentration fell in the very elderly.

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Year:  1974        PMID： 4546946      PMCID： PMC478114          DOI： 10.1136/jcp.27.4.326

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  21 in total

1.  Fibrinolysis related to age in men.

Authors:  H T SWAN
Journal:  Br J Haematol       Date:  1963-07       Impact factor: 6.998

2.  Studies on enhanced fibrinolytic activity in man.

Authors:  S SHERRY; R I LINDEMEYER; A P FLETCHER; N ALKJAERSIG
Journal:  J Clin Invest       Date:  1959-05       Impact factor: 14.808

3.  Studies on the thrombolytic activity of human plasma.

Authors:  W D SAWYER; A P FLETCHER; N ALKJAERSIN; S SHERRY
Journal:  J Clin Invest       Date:  1960-02       Impact factor: 14.808

4.  Partial purification and properties of a proteolytic enzyme of human serum.

Authors:  L F REMMERT; P P COHEN
Journal:  J Biol Chem       Date:  1949-11       Impact factor: 5.157

Review 5.  The Pi system-inherited variants of serum alpha 1-antitrypsin.

Authors:  M K Fagerhol; C B Laurell
Journal:  Prog Med Genet       Date:  1970

6.  "Fibrinolytic capacity" in healthy volunteers at different ages as studied by standardized venous occlusion of arms and legs.

Authors:  B R Robertson; M Pandolfi; I M Nilsson
Journal:  Acta Med Scand       Date:  1972-03

7.  Immunochemical quantitation of antigens by single radial immunodiffusion.

Authors:  G Mancini; A O Carbonara; J F Heremans
Journal:  Immunochemistry       Date:  1965-09

8.  Quantitative estimation of split products of fibrinogen in human serum, relation to diagnosis and treatment.

Authors:  C Merskey; G J Kleiner; A J Johnson
Journal:  Blood       Date:  1966-07       Impact factor: 22.113

9.  The relationship to age and cerebral vascular accidents of fibrin and fibrinolytic activity.

Authors:  R HUME
Journal:  J Clin Pathol       Date:  1961-03       Impact factor: 3.411

10.  Plasma fibrinogen and plasminogen levels in health and in ischaemic heart disease.

Authors:  C M Ogston; D Ogston
Journal:  J Clin Pathol       Date:  1966-07       Impact factor: 3.411
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  4 in total

1.  Serum protein-bound carbohydrates in aging men and women.

Authors:  G Grancińska; K Kozlowska; I Rawicz-Zegrzda
Journal:  Klin Wochenschr       Date:  1977-11-01

2.  The effect of age upon the coagulation system.

Authors:  P J Hamilton; M Allardyce; D Ogston; A A Dawson; A S Douglas
Journal:  J Clin Pathol       Date:  1974-12       Impact factor: 3.411

Review 3.  Pathophysiological Aspects of Aging in Venous Thromboembolism: An Update.

Authors:  Dimitra Akrivou; Garifallia Perlepe; Paraskevi Kirgou; Konstantinos I Gourgoulianis; Foteini Malli
Journal:  Medicina (Kaunas)       Date:  2022-08-10       Impact factor: 2.948

Review 4.  Platelets in aging and cancer-"double-edged sword".

Authors:  Alessandra V S Faria; Sheila S Andrade; Maikel P Peppelenbosch; Carmen V Ferreira-Halder; Gwenny M Fuhler
Journal:  Cancer Metastasis Rev       Date:  2020-09-01       Impact factor: 9.264
  4 in total

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