| Literature DB >> 4545010 |
R F Naegele, A Granoff, R W Darlington.
Abstract
Herpesvirus extracted from a naturally occurring frog renal carcinoma (Lucké tumor) induced virus-free Lucké tumors in developing frogs. Herpesvirus recovered from an induced tumor after incubation at low temperature of tumor fragments cultured in vitro was oncogenic when injected into developing frog embryos. With the exception of the "pure culture" requirement, this experiment fulfills Koch-Henle postulates for the identification of the causative agent of the Lucké tumor.Entities:
Mesh：
Year: 1974 PMID： 4545010 PMCID： PMC388108 DOI： 10.1073/pnas.71.3.830
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205