Literature DB >> 4544147

Comparative tests with formolized and irradiated vaccines against leptospirosis.

B Babudieri, M Castelli, F Pisoni.   

Abstract

The effectiveness of gamma-irradiated antileptospirosis vaccines and of vaccines killed with formol was compared in guineapigs. Irradiated vaccines proved no more effective than formolized vaccines in preventing either death or persistent kidney infection. Anti-pomona vaccines gave little protection against serotype icterohaemorrhagiae, and there was no significant difference between irradiated and formolized preparations. Vaccine prepared from a virulent strain showed little advantage over vaccine prepared from weak strains.

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Year:  1973        PMID: 4544147      PMCID: PMC2482936     

Source DB:  PubMed          Journal:  Bull World Health Organ        ISSN: 0042-9686            Impact factor:   9.408


  5 in total

1.  Laboratory diagnosis of leptospirosis.

Authors:  B BABUDIERI
Journal:  Bull World Health Organ       Date:  1961       Impact factor: 9.408

2.  (CROSS-IMMUNITY STUDIES ON VIRULENT STRAINS OF LEPTOSPIRES BELONGING TO DIFFERENT SEROTYPES.)

Authors:  F KEMENES
Journal:  Z Immunitats Allergieforsch       Date:  1964-08

3.  Vaccination against leptospirosis: protection of hamsters and swine against renal leptospirosis by killed but intact gamma-irradiated or dihydrostreptomycin-exposed Leptospira pomona.

Authors:  O H Stalheim
Journal:  Am J Vet Res       Date:  1967-11       Impact factor: 1.156

4.  Vaccination of hamsters, swine, and cattle with viable, avirulent Leptospira pomona.

Authors:  O H Stalheim
Journal:  Am J Vet Res       Date:  1968-07       Impact factor: 1.156

5.  Studies on immunity in experimental leptospirosis: the immunogenicity of Leptospira icterohemorrhagiae attenuated by gamma-irradiation.

Authors:  W T Hubbert; J N Miller
Journal:  J Immunol       Date:  1965-10       Impact factor: 5.422

  5 in total
  5 in total

1.  Immunogenicity of whole cell and outer envelope leptospiral vaccines in hamsters.

Authors:  R F Bey; N E Auran; R C Johnson
Journal:  Infect Immun       Date:  1974-11       Impact factor: 3.441

2.  Cross-protective immunity against leptospirosis elicited by a live, attenuated lipopolysaccharide mutant.

Authors:  Amporn Srikram; Kunkun Zhang; Thanatchaporn Bartpho; Miranda Lo; David E Hoke; Rasana W Sermswan; Ben Adler; Gerald L Murray
Journal:  J Infect Dis       Date:  2011-01-10       Impact factor: 5.226

3.  Effect of heat or formalin treatment of leptospires on antibody response detected by immunoblotting.

Authors:  V Pope; R C Johnson
Journal:  J Clin Microbiol       Date:  1991-07       Impact factor: 5.948

4.  Effect of heat or chemical treatment on leptospiral antigens.

Authors:  V Pope; R C Johnson
Journal:  J Clin Microbiol       Date:  1987-02       Impact factor: 5.948

Review 5.  The role of nuclear technologies in the diagnosis and control of livestock diseases--a review.

Authors:  Gerrit J Viljoen; Antony G Luckins
Journal:  Trop Anim Health Prod       Date:  2012-10       Impact factor: 1.559

  5 in total

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