Literature DB >> 4542797

Use of ferritin-labelled antibodies for differentiating Leishmania species and other Trypanosomatidae.

V M Saf'janova, A A Avakjan.   

Abstract

A new immunomorphological test for differentiating Leishmania species, based on electron-microscopic revelation of the localization of their specific antigens, is described. The diagnostic value of treating the promastigotes of Leishmania and other Trypanosomatidae with ferritin-labelled antibodies was determined in cross experiments. The immunoferritin test reveals both the serogroup of a given species of Leishmania and specific antigenic differences between different species. However, it fails to differentiate different strains of a given species of Leishmania, which attests to its species-specificity.

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Year:  1973        PMID: 4542797      PMCID: PMC2481067     

Source DB:  PubMed          Journal:  Bull World Health Organ        ISSN: 0042-9686            Impact factor:   9.408


  10 in total

Review 1.  LEISHMANIA.

Authors:  S ADLER
Journal:  Adv Parasitol       Date:  1964       Impact factor: 3.870

2.  Preparation of an electron-dense antibody conjugate.

Authors:  S J SINGER
Journal:  Nature       Date:  1959-05-30       Impact factor: 49.962

3.  THE PROPERTIES OF SPECIFIC STAINS FOR ELECTRON MICROSCOPY PREPARED BY THE CONJUGATION OF ANTIBODY MOLECULES WITH FERRITIN.

Authors:  S J Singer; A F Schick
Journal:  J Biophys Biochem Cytol       Date:  1961-03-01

4.  [Study of Trypanosoma equiperdum with the electron microscope after action of homologous antibodies labeled with ferritin].

Authors:  M E Boisson; R Masseyeff; C Boisson; X Mattei; M C Zisswiller; A Tchabi
Journal:  C R Seances Soc Biol Fil       Date:  1969-02-08

5.  [Diagnostic value of the method of treatment of Leishmania with ferritin-labelled antibody for comparative electron microscopic study].

Authors:  A A Avakian; V M Saf'ianova; B A Koshelev
Journal:  Med Parazitol (Mosk)       Date:  1972 Jan-Feb

6.  [Methods for evaluating the degree of antigenic relationship of different strains of Leishmania].

Authors:  V M Saf'ianova; E I Aliev
Journal:  Med Parazitol (Mosk)       Date:  1971 May-Jun

7.  Localization of variable antigens in the surface coat of Trypanosoma brucei using ferritin conjugated antibody.

Authors:  K Vickerman; A G Luckins
Journal:  Nature       Date:  1969-12-13       Impact factor: 49.962

8.  Pellicular microtubules in the family Trypanosomatidae.

Authors:  E Angelopoulos
Journal:  J Protozool       Date:  1970-02

9.  [Comparative study of antigenic properties and virulence of Leishmania in relation to time of cultivation in vitro].

Authors:  E I Aliev
Journal:  Med Parazitol (Mosk)       Date:  1970 May-Jun

10.  [Comparative study of pathological process caused by Leishmania tropica major and Leishmania tropica minor strains of golden hamsters].

Authors:  E I Aliev
Journal:  Med Parazitol (Mosk)       Date:  1971 Mar-Apr
  10 in total
  1 in total

1.  The genome of Leishmania adleri from a mammalian host highlights chromosome fission in Sauroleishmania.

Authors:  Simone Coughlan; Peter Mulhair; Mandy Sanders; Gabriele Schonian; James A Cotton; Tim Downing
Journal:  Sci Rep       Date:  2017-03-03       Impact factor: 4.379

  1 in total

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