Literature DB >> 45401

Nuclear magnetic resonance determinations of permeation coefficients for maleic acid in phospholipid vesicles.

J H Prestegard, J A Cramer, D B Viscio.   

Abstract

Lipid bilayer permeation coefficients for the neutral maleic acid molecule and the maleate monoanion have been determined by proton magnetic resonance techniques. Phosphatiydylcholine-cholesterol (2:1) unilamellar vesicles were prepared having an initial maleate anion concentration gradient stabilized by coupling to an impermeant potassium counterion. The coupling was released by addition of valinomycin, and the time evolution of external pH, internal pH, and maleate concentration followed using nuclear magnetic resonance areas and chemical shifts. Transport rate equations were numerically integrated to fit the date, yielding best fit permeation coefficients of 4 X 10(-9) and 4 X 10(-5) cm/s for maleate monoanion and maleic acid, respectively.

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Year:  1979        PMID： 45401      PMCID： PMC1328571          DOI： 10.1016/s0006-3495(79)85272-8

Source DB:  PubMed          Journal:  Biophys J        ISSN： 0006-3495            Impact factor:   4.033


  8 in total

1.  Spectator-ion effect on the passage of ions through membranes.

Authors:  J J Kozak
Journal:  Proc Natl Acad Sci U S A       Date:  1975-02       Impact factor: 11.205

2.  Internal pH of isolated chromaffin vesicles.

Authors:  R G Johnson; A Scarpa
Journal:  J Biol Chem       Date:  1976-04-10       Impact factor: 5.157

Review 3.  The action of uncouplers on lipid bilayer membranes.

Authors:  B Neumcke
Journal:  Membranes       Date:  1975

4.  Catecholamine uptake and concentration by liposomes maintaining p/ gradients.

Authors:  J W Nichols; D W Deamer
Journal:  Biochim Biophys Acta       Date:  1976-11-11

5.  NMR studies of pH-induced transport of carboxylic acids across phospholipid vesicle membranes.

Authors:  J A Cramer; J H Prestegard
Journal:  Biochem Biophys Res Commun       Date:  1977-03-21       Impact factor: 3.575

6.  CHROMATOGRAPHICALLY HOMOGENEOUS LECITHIN FROM EGG PHOSPHOLIPIDS.

Authors:  W S SINGLETON; M S GRAY; M L BROWN; J L WHITE
Journal:  J Am Oil Chem Soc       Date:  1965-01       Impact factor: 1.849

7.  Cholesterol-phosphatidylcholine interactions in vesicle systems. Implication of vesicle size and proton magnetic resonance line-width changes.

Authors:  M P Gent; J H Prestegard
Journal:  Biochemistry       Date:  1974-09-10       Impact factor: 3.162

Review 8.  The carrier potential of liposomes in biology and medicine (second of two parts).

Authors:  G Gregoriadis
Journal:  N Engl J Med       Date:  1976-09-30       Impact factor: 91.245
  8 in total
  4 in total

1.  Employing permeability coefficients to understand the biomobility and bioaccumulation of compounds sensitive to the environment.

Authors:  W R Cullen; F G Herring; J C Nelson
Journal:  Bull Environ Contam Toxicol       Date:  1994-02       Impact factor: 2.151

2.  Determination of catecholamine permeability coefficients for passive diffusion across phospholipid vesicle membranes.

Authors:  A Bochain; L Estey; G Haronian; M Reale; C Rojas; J Cramer
Journal:  J Membr Biol       Date:  1981-05-15       Impact factor: 1.843

3.  pH gradients across phospholipid membranes caused by fast flip-flop of un-ionized fatty acids.

Authors:  F Kamp; J A Hamilton
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-01       Impact factor: 11.205

4.  NMR studies of 5-hydroxytryptamine transport through large unilamellar vesicle membranes.

Authors:  D B Viscio; J H Prestegard
Journal:  Proc Natl Acad Sci U S A       Date:  1981-03       Impact factor: 11.205
  4 in total

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