Literature DB >> 4530297

Carbon-13 nuclear magnetic resonance spectroscopy. Structure of the anticoagulant warfarin and related compounds in solution.

D D Giannini, K K Chan, J D Roberts.   

Abstract

Carbon-13 nuclear magnetic resonance spectra have been obtained for the coumarin-related compounds warfarin and phenprocoumon. The spectral assignments indicate that warfarin exists as a mixture of cyclic hemiketal diastereomers in dimethyl sulfoxide solution. The sodium salt of warfarin exists as the ringopen form in water solution.

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Year:  1974        PMID: 4530297      PMCID: PMC434362          DOI: 10.1073/pnas.71.10.4221

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  2 in total

1.  The structure of dicoumarol and related compounds.

Authors:  D W Hutchinson; J A Tomlinson
Journal:  Tetrahedron       Date:  1969-06       Impact factor: 2.457

2.  Nuclear magnetic resonance spectroscopy. 13 C Fourier transform spectra of 8 - and 9 -tetrahydrocannabinol.

Authors:  B L Hawkins; J D Roberts
Journal:  Proc Natl Acad Sci U S A       Date:  1973-04       Impact factor: 11.205

  2 in total
  2 in total

1.  Multiple UDP-glucuronosyltransferases in human liver microsomes glucuronidate both R- and S-7-hydroxywarfarin into two metabolites.

Authors:  C Preston Pugh; Dakota L Pouncey; Jessica H Hartman; Robert Nshimiyimana; Linda P Desrochers; Thomas E Goodwin; Gunnar Boysen; Grover P Miller
Journal:  Arch Biochem Biophys       Date:  2014-10-19       Impact factor: 4.013

2.  Evaluation of alternatives to warfarin as probes for Sudlow site I of human serum albumin: characterization by high-performance affinity chromatography.

Authors:  K S Joseph; Annette C Moser; Sara B G Basiaga; John E Schiel; David S Hage
Journal:  J Chromatogr A       Date:  2008-10-01       Impact factor: 4.759

  2 in total

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