Literature DB >> 4528633

Long pyrimidine tracts of L-cell DNA: localization to repeated DNA.

N A Straus, H C Birnboim.   

Abstract

Like HeLa DNA, L-cell DNA contains a significant number of unexpectedly long pyrimidine tracts. 1.3% of the thymidine residues of L-cell DNA are found in these long polypyrimidine tracts. Analysis of L-cell DNA fractions with different rates of reassociation indicates that polypyrimidine tracts are associated with "repeated" DNA. Longer pyrimidine tracts appear to have a higher repetition frequency than shorter tracts, and some may be repeated as many as 5 x 10(4) times in L-cell DNA.

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Year:  1974        PMID: 4528633      PMCID: PMC388605          DOI: 10.1073/pnas.71.8.2992

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  3 in total

1.  SEDIMENTATION STUDIES OF THE SIZE AND SHAPE OF DNA.

Authors:  F W STUDIER
Journal:  J Mol Biol       Date:  1965-02       Impact factor: 5.469

2.  Repeated sequences in DNA. Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms.

Authors:  R J Britten; D E Kohne
Journal:  Science       Date:  1968-08-09       Impact factor: 47.728

3.  Analysis of long pyrimidine polynucleotides in HeLa cell nuclear DNA: absence of polydeoxythymidylate.

Authors:  H C Birnboim; R E Mitchel; N A Straus
Journal:  Proc Natl Acad Sci U S A       Date:  1973-08       Impact factor: 11.205

  3 in total
  1 in total

1.  The structural organization of mouse metaphase chromosomes.

Authors:  R R Schreck; V G Dev; B F Erlanger; O J Miller
Journal:  Chromosoma       Date:  1977-07-18       Impact factor: 4.316

  1 in total

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