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Literature DB >> 4517670

Guanosine 5'-diphosphate, 3'-diphosphate: assignment of structure by 13C nuclear magnetic resonance spectroscopy.

L Que, G R Willie, M Cashel, J W Bodley, G R Gray.

Abstract

Guanosine tetraphosphate, recently discovered to mediate the regulatory relationship between protein synthesis and RNA accumulation in various bacteria, has been synthesized in vitro in large quantities and analyzed by natural-abundance (13)C nuclear magnetic resonance spectroscopy in order to confirm its structure and establish the positions of phosphate attachment. These studies have established its structure as guanosine 5'-diphosphate, 3'-diphosphate.

Entities: Chemical

Mesh：

Substances：

Year: 1973 PMID： 4517670 PMCID： PMC427056 DOI： 10.1073/pnas.70.9.2563

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

23 in total

1. The control of ribonucleic acid synthesis in Escherichia coli. V. Characterization of a nucleotide associated with the stringent response.

Authors: M Cashel; B Kalbacher
Journal: J Biol Chem Date: 1970-05-10 Impact factor: 5.157

2. On the regulation of guanosine tetraphosphate levels in stringent and relaxed strains of Escherichia coli.

Authors: R A Lazzarini; M Cashel; J Gallant
Journal: J Biol Chem Date: 1971-07-25 Impact factor: 5.157

3. The mechanism of amino acid control of guanylate and adenylate biosynthesis.

Authors: J Gallant; J Irr; M Cashel
Journal: J Biol Chem Date: 1971-09-25 Impact factor: 5.157

4. Two compounds implicated in the function of the RC gene of Escherichia coli.

Authors: M Cashel; J Gallant
Journal: Nature Date: 1969-03-01 Impact factor: 49.962

Review 5. Physiology and genetics of the "ribonucleic acid control" locus in escherichia coli.

Authors: G Edlin; P Broda
Journal: Bacteriol Rev Date: 1968-09

6. Polarity in relaxed strains of Salmonella typhimurium.

Authors: R G Martin
Journal: J Mol Biol Date: 1968-01-14 Impact factor: 5.469

7. The control of ribonucleic acid synthesis in Escherichia coli. IV. Relevance of unusual phosphorylated compounds from amino acid-starved stringent strains.

Authors: M Cashel
Journal: J Biol Chem Date: 1969-06-25 Impact factor: 5.157

Guanosine 5'-diphosphate, 3'-diphosphate: assignment of structure by 13C nuclear magnetic resonance spectroscopy.

1. The control of ribonucleic acid synthesis in Escherichia coli. V. Characterization of a nucleotide associated with the stringent response.

2. On the regulation of guanosine tetraphosphate levels in stringent and relaxed strains of Escherichia coli.

3. The mechanism of amino acid control of guanylate and adenylate biosynthesis.

4. Two compounds implicated in the function of the RC gene of Escherichia coli.

Review 5. Physiology and genetics of the "ribonucleic acid control" locus in escherichia coli.

6. Polarity in relaxed strains of Salmonella typhimurium.

7. The control of ribonucleic acid synthesis in Escherichia coli. IV. Relevance of unusual phosphorylated compounds from amino acid-starved stringent strains.

8. Carbon-13 magnetic resonance. XVII. Pyrimidine and purine nucleosides.

9. Nuclear magnetic resonance spectroscopy: 13C spectra of some common nucleotides.

10. Isolation and characterization of an RNA relaxed mutant of B. subtilis.

1. Nucleotide pools and regulation of ribonucleic acid synthesis in yeast.

2. Fermentative accumulation of guanosine polyphosphates by Brevibacterium ammoniagenes.

3. Role of guanine nucleotides in protein synthesis. Elongation factor G and guanosine 5'-triphosphate,3'-diphosphate.