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Literature DB >> 4516211

HL-A-linked human immune-response genes.

C E Buckley, F C Dorsey, R B Corley, W B Ralph, M A Woodbury, D B Amos.

Abstract

Genetic control of the response to specific natural-product antigens has been documented in three informative families. Families were selected on the basis of probands with tuberculosarcoidosis, chronic cutaneous moniliasis, and rheumatoid arthritis. An increased incidence of delayed cutaneous unresponsiveness was observed in each family. Positive associations were identified between HL-A haplotypes and immediate cutaneous hypersensitivity responses to 5, 8, and 11 of 23 test antigens in the three respective families. HL-A-associated differences in averaged responses of cutaneous hypersensitivity were excluded. These significant associations are consistent with linkage between HL-A haplotypes and genes responsible for the immune response to various natural-product antigens.

Entities: Disease Species

Mesh：

Substances：

Year: 1973 PMID： 4516211 PMCID： PMC433687 DOI： 10.1073/pnas.70.7.2157

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

21 in total

1. QUANTITATIVE STUDIES ON THE ASSAY OF HUMAN SKIN-SENSITIZING ANTIBODIES (REAGINS). I. AN EXAMINATION OF FACTORS AFFECTING THE ACCURACY OF THE PRAUSNITZ-KUESTNER (P-K) TEST.

Authors: D R STANWORTH; W J KUHNS
Journal: Immunology Date: 1965-04 Impact factor: 7.397

2. Regulation of homocytotropic antibody formation in the rat. VI. Inhibitory effect of thymocytes on the homocytotropic antibody response.

Authors: K Okumura; T Tada
Journal: J Immunol Date: 1971-12 Impact factor: 5.422

Review 3. Primary immunodeficiencies. Report of a World Health Organization Committee.

Authors: H Fudenberg; R A Good; H C Goodman; W Hitzig; H G Kunkel; I M Roitt; F S Rosen; D S Rowe; M Seligmann; J R Soothill
Journal: Pediatrics Date: 1971-05 Impact factor: 7.124

Review 4. Genetic control of specific immune responses.

Authors: H O McDevitt; B Benacerraf
Journal: Adv Immunol Date: 1969 Impact factor: 3.543

5. Serum immunoglobulin levels throughout the life-span of healthy man.

Authors: C E Buckley; F C Dorsey
Journal: Ann Intern Med Date: 1971-11 Impact factor: 25.391

6. Identifying the tuberculous infected. The dual-test technique.

Authors: C E Palmer; L B Edwards
Journal: JAMA Date: 1968-07-15 Impact factor: 56.272

7. Relationship between histocompatibility (H-2) genotype and immune responsiveness to low doses of ovalbumin in the mouse.

Authors: N M Vaz; E M Vaz; B B Levine
Journal: J Immunol Date: 1970-06 Impact factor: 5.422

8. "Vibes".

Authors: L Thomas
Journal: N Engl J Med Date: 1972-01-13 Impact factor: 91.245

9. Antigenicity of polypeptides (poly alpha amino acids). XV. Studies on the immunogenicity of synthetic polypeptides in mice.

Authors: P Pinchuck; P H Maurer
Journal: J Exp Med Date: 1965-10-01 Impact factor: 14.307

10. A major genetic locus affecting resistance to infection with murine leukemia viruses. II. Apparent identity to a major locus described for resistance to friend murine leukemia virus.

Authors: T Pincus; W P Rowe; F Lilly
Journal: J Exp Med Date: 1971-06-01 Impact factor: 14.307

10 in total

HL-A-linked human immune-response genes.

1. QUANTITATIVE STUDIES ON THE ASSAY OF HUMAN SKIN-SENSITIZING ANTIBODIES (REAGINS). I. AN EXAMINATION OF FACTORS AFFECTING THE ACCURACY OF THE PRAUSNITZ-KUESTNER (P-K) TEST.

2. Regulation of homocytotropic antibody formation in the rat. VI. Inhibitory effect of thymocytes on the homocytotropic antibody response.

Review 3. Primary immunodeficiencies. Report of a World Health Organization Committee.

Review 4. Genetic control of specific immune responses.

5. Serum immunoglobulin levels throughout the life-span of healthy man.

6. Identifying the tuberculous infected. The dual-test technique.

7. Relationship between histocompatibility (H-2) genotype and immune responsiveness to low doses of ovalbumin in the mouse.

8. "Vibes".

9. Antigenicity of polypeptides (poly alpha amino acids). XV. Studies on the immunogenicity of synthetic polypeptides in mice.

10. A major genetic locus affecting resistance to infection with murine leukemia viruses. II. Apparent identity to a major locus described for resistance to friend murine leukemia virus.

1. Lymphocyte response to IgG in patients with ankylosing spondylitis and their families.

2. HL-A frequencies in Down's syndrome.

3. HL-A antigens in North American black families.

4. The major histocompatibility complex--comparison in the mouse, man, and the rat. A review.

5. A new antigen system expressed in human endothelial cells.

6. Immunologic and genetic factors influencing reproduction. A review.

7. The genetic control of the antibody response in inbred rats.

8. Reactivity to spherule-derived coccidioidin in the southeastern United States.

9. Mapping of the immune response genes in the major histocompatibility complex of the Rhesus monkey.

10. Association of HL-A 5 and immune responsiveness in vitro to streptococcal antigens.