Literature DB >> 451573

Dynamic changes in circulating 1,25-dihydroxyvitamin D during reproduction in rats.

J W Pike, J B Parker, M R Haussler, A Boass, S V Toverud.   

Abstract

The concentrations of 1,25-dihydroxyvitamin D [1,25-(OH)2D], calcium, and phosphorus were measured in the serum of rats during pregnancy and at various stages of lactation. The concentration of 1,25-(OH)2D hormone increased almost two-fold during pregnancy and the latter part of lactation, but decreased to control levels or very low values immediately after birth and weaning, respectively. Furthermore, the concentration of 1,25-(OH)2D was inversely correlated with the concentration of calcium, suggesting that circulating 1,25-(OH)2D fluctuates in concert with calcium demands during the reproductive cycle. Parathyroidectomy in lactating rats caused a 70 percent inhibition of the normally observed 1,25-(OH)2D increase, indicating that parathyroid hormone, in response to changes in serum calcium, is a primary modulator of 1,25-(OH)2D during lactation.

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Year:  1979        PMID： 451573     DOI： 10.1126/science.451573

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  10 in total

Review 1.  Vitamin D and the kidney.

Authors:  Rajiv Kumar; Peter J Tebben; James R Thompson
Journal:  Arch Biochem Biophys       Date:  2012-03-15       Impact factor: 4.013

2.  Effects of experimental diabetes on the vitamin D metabolism of pregnant rats and their fetuses.

Authors:  J Demignon; C Rebut-Bonneton
Journal:  Calcif Tissue Int       Date:  1988-02       Impact factor: 4.333

3.  Calcitonin is a major regulator for the expression of renal 25-hydroxyvitamin D3-1alpha-hydroxylase gene in normocalcemic rats.

Authors:  T Shinki; Y Ueno; H F DeLuca; T Suda
Journal:  Proc Natl Acad Sci U S A       Date:  1999-07-06       Impact factor: 11.205

Review 4.  Vitamin D and intestinal calcium absorption.

Authors:  Sylvia Christakos; Puneet Dhawan; Angela Porta; Leila J Mady; Tanya Seth
Journal:  Mol Cell Endocrinol       Date:  2011-06-01       Impact factor: 4.102

5.  The impact of mammalian reproduction on cancellous bone architecture.

Authors:  S M Shahtaheri; J E Aaron; D R Johnson; S K Paxton
Journal:  J Anat       Date:  1999-04       Impact factor: 2.610

6.  Evidence for a role of prolactin in calcium homeostasis: regulation of intestinal transient receptor potential vanilloid type 6, intestinal calcium absorption, and the 25-hydroxyvitamin D(3) 1alpha hydroxylase gene by prolactin.

Authors:  Dare V Ajibade; Puneet Dhawan; Adam J Fechner; Mark B Meyer; J Wesley Pike; Sylvia Christakos
Journal:  Endocrinology       Date:  2010-05-12       Impact factor: 4.736

7.  Bone calcium turnover, formation, and resorption in bromocriptine- and prolactin-treated lactating rats.

Authors:  Sutada Lotinun; Liangchai Limlomwongse; Vorachai Sirikulchayanonta; Nateetip Krishnamra
Journal:  Endocrine       Date:  2003 Feb-Mar       Impact factor: 3.633

8.  Vitamin D metabolism during pregnancy and lactation in the rat.

Authors:  B P Halloran; E N Barthell; H F DeLuca
Journal:  Proc Natl Acad Sci U S A       Date:  1979-11       Impact factor: 11.205

9.  Vitamin D metabolism in pregnant and pseudopregnant rats: identification of 25-hydroxycholecalciferol-1-hydroxylase in decidual tissue.

Authors:  M S Nanes
Journal:  Calcif Tissue Int       Date:  1988-06       Impact factor: 4.333

10.  Calcium restriction during lactation has minimal effects on post-weaning mineral metabolism and bone recovery.

Authors:  Ryan D Ross; Matthew J Meagher; D Rick Sumner
Journal:  J Bone Miner Metab       Date:  2018-10-25       Impact factor: 2.626
  10 in total

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