Literature DB >> 451551

Nitrite promotes lymphoma incidence in rats.

P M Newberne.   

Abstract

Rats were exposed to sodium nitrite in food or water at concentrations of 0, 250, 1000, and 2000 parts per million. Lymphoma was increased in all groups fed nitrite; the overall combined incidence was 5.4 percent in 573 control rats and 10.2 percent in 1383 treated rats. The mechanism of cancer induction did not appear to be through the formation of nitrosamines but through a more direct effect of nitrite on the lymphocyte.

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Year:  1979        PMID: 451551     DOI: 10.1126/science.451551

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  7 in total

1.  Nisin: a possible alternative or adjunct to nitrite in the preservation of meats.

Authors:  M K Rayman; B Aris; A Hurst
Journal:  Appl Environ Microbiol       Date:  1981-02       Impact factor: 4.792

2.  Sex habits, recent disease, and drug use in two groups of Danish male homosexuals.

Authors:  P Ebbesen; M Melbye; R J Biggar
Journal:  Arch Sex Behav       Date:  1984-08

Review 3.  Dysfunction of nitric oxide synthases as a cause and therapeutic target in delayed cerebral vasospasm after SAH.

Authors:  R M Pluta
Journal:  Acta Neurochir Suppl       Date:  2008

4.  Histiocytic sarcoma with a granuloma-like component occurring in a large colony of Sprague-Dawley rats.

Authors:  R A Squire; K M Brinkhous; S C Peiper; H I Firminger; R B Mann; J D Strandberg
Journal:  Am J Pathol       Date:  1981-10       Impact factor: 4.307

5.  A carcinogenic potency database of the standardized results of animal bioassays.

Authors:  L S Gold; C B Sawyer; R Magaw; G M Backman; M de Veciana; R Levinson; N K Hooper; W R Havender; L Bernstein; R Peto
Journal:  Environ Health Perspect       Date:  1984-12       Impact factor: 9.031

6.  Effects of combined treatment with phenolic compounds and sodium nitrite on two-stage carcinogenesis and cell proliferation in the rat stomach.

Authors:  M Kawabe; K Takaba; Y Yoshida; M Hirose
Journal:  Jpn J Cancer Res       Date:  1994-01

Review 7.  The relationship between consumption of nitrite or nitrate and risk of non-Hodgkin lymphoma.

Authors:  Mengxia Yu; Chenying Li; Chao Hu; Jingrui Jin; Shenxian Qian; Jie Jin
Journal:  Sci Rep       Date:  2020-01-17       Impact factor: 4.379

  7 in total

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