Literature DB >> 4514310

The reaction of N-iodosuccinimide with the goitrogens: a model for the active iodine of the thyroid gland.

L Jirousek, M Soodak.   

Abstract

The reactivities of N-iodosuccinimide and iodine with various goitrogenic compounds were studied with dimethylsulfoxide through which nitrogen had been bubbled as a solvent. Although iodine does not react with all of the compounds, N-iodosuccinimide does react with all of them. N-Iodosuccinimide may, therefore, serve as an interesting model for the "active iodine" of the thyroid.

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Year:  1973        PMID: 4514310      PMCID: PMC433506          DOI: 10.1073/pnas.70.5.1401

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  6 in total

1.  Iodide peroxidase in rat thyroid and salivary glands and its inhibition by antithyroid compounds.

Authors:  N M ALEXANDER
Journal:  J Biol Chem       Date:  1959-06       Impact factor: 5.157

2.  Thioacetamide, an anti-thyroid compound.

Authors:  F MALOOF; M SOODAK
Journal:  Endocrinology       Date:  1961-01       Impact factor: 4.736

3.  The effect of compounds allied to resorcinol upon the uptake of radioactive iodine (131I) by the thyroid of the rat.

Authors:  D G ARNOTT; I DONIACH
Journal:  Biochem J       Date:  1952-02       Impact factor: 3.857

Review 4.  Thyroid peroxidase and thyroxine biosynthesis.

Authors:  A Taurog
Journal:  Recent Prog Horm Res       Date:  1970

5.  The oxidative cleavage of tyrosyl-peptide bonds during iodination.

Authors:  H Junek; K L Kirk; L A Cohen
Journal:  Biochemistry       Date:  1969-05       Impact factor: 3.162

6.  The action of 1,1,3-tricyano-2-amino-1-propene (U-9189) on the thyroid gland of the rat and its effects in human thyrotoxicosis.

Authors:  S H INGBAR
Journal:  J Clin Endocrinol Metab       Date:  1961-02       Impact factor: 5.958

  6 in total

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