Literature DB >> 4510816

Treatment of acute myeloblastic leukaemia with RP 22050.

C Jacquillat, M Weil, M F Gemon, V Izrael, G Schaison, M Boiron, J Bernard.   

Abstract

Fourty-four patients with acute myeloblastic leukaemia were treated with RP 22050, a new, semisynthetic derivative of daunorubicin. Complete remissions were achieved in 20 patients (45%). The median dose given was 23 mg/kg. The toxicity of RP 22050 is mainly haematological. Resistance rather than death in aplasia seemed to be the cause of failure of therapy.

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Year:  1972        PMID: 4510816      PMCID: PMC1786703          DOI: 10.1136/bmj.4.5838.468

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  2 in total

1.  Arabinosyl cytosine: a useful agent in the treatment of acute leukemia in adults.

Authors:  R R Ellison; J F Holland; M Weil; C Jacquillat; M Boiron; J Bernard; A Sawitsky; F Rosner; B Gussoff; R T Silver; A Karanas; J Cuttner; C L Spurr; D M Hayes; J Blom; L A Leone; F Haurani; R Kyle; J L Hutchison; R J Forcier; J H Moon
Journal:  Blood       Date:  1968-10       Impact factor: 22.113

2.  Clinical evaluation of adriamycin, a new antitumour antibiotic.

Authors:  G Bonadonna; S Monfardini; M De Lena; F Fossati-Bellani
Journal:  Br Med J       Date:  1969-08-30
  2 in total
  3 in total

1.  Depression of cellular immunity in pregnancy due to a serum factor.

Authors:  C A Hill; R Finn; V Denye
Journal:  Br Med J       Date:  1973-09-08

2.  A survey of the anthracycline derivatives in hematology.

Authors:  C Jacquillat; M Weil; M F Auclerc; J Maral; G Schaison; M Boiron; J Bernard
Journal:  Cancer Chemother Pharmacol       Date:  1979       Impact factor: 3.333

3.  Rubidazone vs adriamycin: an evaluation of their differential toxicity in the spleen colony assay system.

Authors:  D S Alberts; T Van Daalen Wetters
Journal:  Br J Cancer       Date:  1976-07       Impact factor: 7.640

  3 in total

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