Literature DB >> 4510295

Microinjection of rabbit hemoglobin messenger RNA into amphibian oocytes and embryos.

J Brachet, G Huez, E Hubert.   

Abstract

After microinjection of hemoglobin mRNA from rabbit reticulocytes (9S mRNA) into Xenopus laevis oocytes, the cytological structure remains normal. The peroxidase reaction does not show an accumulation of synthesized hemoglobin in the germinal vesicle. Fertilized Pleurodeles Waltlii eggs synthesize rabbit hemoglobin after injection of 9S mRNA; hemoglobin synthesis decreases as development progresses. Micromeres and macromeres synthesize equal amounts of hemoglobin, despite the fact that the micromeres contain many more ribosomes. Descendants of injected blastomeres divide more slowly and do not differentiate; they ultimately undergo cytolysis.

Entities:  

Mesh:

Substances:

Year:  1973        PMID: 4510295      PMCID: PMC433302          DOI: 10.1073/pnas.70.2.543

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  10 in total

1.  CHROMOSOME COMPLEMENTS OF RANA PIPIENS EMBRYOS DEVELOPING FROM EGGS INJECTED WITH PROTEIN FROM ADULT LIVER CELLS.

Authors:  H URSPRUNG; C L MARKERT
Journal:  Dev Biol       Date:  1963-12       Impact factor: 3.582

2.  Differentiation of cells of the Rana pipiens gastrula in unconditioned medium.

Authors:  L G BARTH; L J BARTH
Journal:  J Embryol Exp Morphol       Date:  1959-06

3.  Observations on the physico-chemical properties of isolated nuclei.

Authors:  J HOLTFRETER
Journal:  Exp Cell Res       Date:  1954-08       Impact factor: 3.905

4.  Use of frog eggs and oocytes for the study of messenger RNA and its translation in living cells.

Authors:  J B Gurdon; C D Lane; H R Woodland; G Marbaix
Journal:  Nature       Date:  1971-09-17       Impact factor: 49.962

5.  Release of messenger RNA from rabbit reticulocyte polyribosomes at low concentration of divalent cations.

Authors:  G Huez; A Burny; G Marbaix; B Lebleu
Journal:  Biochim Biophys Acta       Date:  1967

6.  Studies on nucleocytoplasmic interactions during early amphibian development. I. Localized destruction of the egg cortex.

Authors:  J Brachet; E Hubert
Journal:  J Embryol Exp Morphol       Date:  1972-02

7.  Rabbit haemoglobin synthesis in frog cells. II. Further characterization of the products of translation of reticulocyte 9 s RNA.

Authors:  G Marbaix; C D Lane
Journal:  J Mol Biol       Date:  1972-06-28       Impact factor: 5.469

8.  Rabbit haemoglobin synthesis in frog cells: the translation of reticulocyte 9 s RNA in frog oocytes.

Authors:  C D Lane; G Marbaix; J B Gurdon
Journal:  J Mol Biol       Date:  1971-10-14       Impact factor: 5.469

9.  [Deoxyribonucleic acids in lethal hybrids of sea urchins].

Authors:  J Brachet; N Hulin
Journal:  Exp Cell Res       Date:  1970-06       Impact factor: 3.905

10.  Gene expression in interspecific hybrids. I. DNA synthesis in the lethal cross Arbacia lixula male X Paracentrotus lividus female.

Authors:  H Denis; J Brachet
Journal:  Proc Natl Acad Sci U S A       Date:  1969-01       Impact factor: 11.205

  10 in total
  2 in total

Review 1.  mRNA vaccine: a potential therapeutic strategy.

Authors:  Yang Wang; Ziqi Zhang; Jingwen Luo; Xuejiao Han; Yuquan Wei; Xiawei Wei
Journal:  Mol Cancer       Date:  2021-02-16       Impact factor: 27.401

Review 2.  mRNA vaccines for COVID-19 and diverse diseases.

Authors:  Abid Hussain; Haiyin Yang; Mengjie Zhang; Qing Liu; Ghallab Alotaibi; Muhammad Irfan; Huining He; Jin Chang; Xing-Jie Liang; Yuhua Weng; Yuanyu Huang
Journal:  J Control Release       Date:  2022-03-21       Impact factor: 11.467

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.