Literature DB >> 4508331

Conformational relationships between analogs of acetylcholine and those of local anesthetics in solution.

A Makriyannis, R F Sullivan, H G Mautner.   

Abstract

Conformations of analogs of acetylcholine and of related local anesthetics, in which either of the oxygen atoms had been replaced by other heteroatoms, were studied in solution by nuclear magnetic resonance. Several correlations between structure and conformation could be made.

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Year:  1972        PMID： 4508331      PMCID： PMC389783          DOI： 10.1073/pnas.69.11.3416

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  14 in total

1.  Conformational requirements of acetylcholine analogues and local anaesthetics.

Authors:  H G Mautner; D D Dexter; B W Low
Journal:  Nat New Biol       Date:  1972-07-19

2.  The conformation of acetylcholine and related compounds in aqueous solution as studied by nuclear magnetic resonance spectroscopy.

Authors:  P Partington; J Feeney; A S Burgen
Journal:  Mol Pharmacol       Date:  1972-05       Impact factor: 4.436

3.  Sulfur and selenium compounds related to acetylcholine and choline. VII. Isologs of benzoylthionocholine and of 2-dimethylaminoethyl thionobenzoate.

Authors:  S H Chu; H G Mautner
Journal:  J Med Chem       Date:  1968-05       Impact factor: 7.446

4.  Molecular properties of local anesthetics: the crystal structure of procaine hydrochloride.

Authors:  R Beall; J Herdklotz; R L Sass
Journal:  Biochem Biophys Res Commun       Date:  1970-05-11       Impact factor: 3.575

5.  Molecular structure determining the action of local anesthetics on the acetylcholine receptor.

Authors:  E Bartels; D Nachmansohn
Journal:  Biochem Z       Date:  1965-08-19

6.  Relationship between acetylcholine and local anesthetics.

Authors:  E Bartels
Journal:  Biochim Biophys Acta       Date:  1965-09-27

7.  Structure of acetylcholine and other substrates of cholinergic systems.

Authors:  F G Canepa; P Pauling; H Sörum
Journal:  Nature       Date:  1966-05-28       Impact factor: 49.962

8.  Acetylcholine and its thiolester and selenolester analogs: conformation, electron distribution, and biological activity.

Authors:  E Shefter; H G Mautner
Journal:  Proc Natl Acad Sci U S A       Date:  1969-08       Impact factor: 11.205

9.  Sulfur and selenium compounds related to acetylcholine and choline. 11. Selenocarbonyl ester and selenocarboxamide analogs of local anesthetics.

Authors:  S H Chu; G R Hillman; H G Mautner
Journal:  J Med Chem       Date:  1972-07       Impact factor: 7.446
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  2 in total

Review 1.  End-plate acetylcholine receptor: structure, mechanism, pharmacology, and disease.

Authors:  Steven M Sine
Journal:  Physiol Rev       Date:  2012-07       Impact factor: 37.312

2.  Acetylcholine-like molecular arrangement in psychomimetic anticholinergic drugs.

Authors:  S Maayani; H Weinstein; S Cohen; M Sokolovsky
Journal:  Proc Natl Acad Sci U S A       Date:  1973-11       Impact factor: 11.205
  2 in total

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