Literature DB >> 4506758

Assays for porphyrins, delta-aminolevulinic-acid dehydratase, and porphyrinogen synthetase in microliter samples of whole blood: applications to metabolic defects involving the heme pathway.

S Granick, S Sassa, J L Granick, R D Levere, A Kappas.   

Abstract

Three micromethods are described for the assay of enzymes or products of the heme biosynthetic pathway in blood. A fluorometric method for the assay of protoporphyrin may be applied to the rapid screening of children for chronic lead poisoning. A colorimetric assay for delta-aminolevulinic-acid dehydratase may be applied to the detection of acute and chronic lead poisoning. A fluorometric assay for porphyrin formation from prophobilinogen is also described.

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Year:  1972        PMID： 4506758      PMCID： PMC426945          DOI： 10.1073/pnas.69.9.2381

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  8 in total

Review 1.  DISTURBANCES IN THE BIOSYNTHESIS OF HEME IN LEAD INTOXICATION.

Authors:  J J CHISOLM
Journal:  J Pediatr       Date:  1964-02       Impact factor: 4.406

2.  The occurrence and determination of delta-amino-levulinic acid and porphobilinogen in urine.

Authors:  D MAUZERALL; S GRANICK
Journal:  J Biol Chem       Date:  1956-03       Impact factor: 5.157

3.  Porphyria.

Authors:  C J WATSON
Journal:  Adv Intern Med       Date:  1954

4.  Spectral-absorption coefficients of some porphyrins in the Soret-band region.

Authors:  C Rimington
Journal:  Biochem J       Date:  1960-06       Impact factor: 3.857

5.  Intermittent acute porphyria--demonstration of a genetic defect in porphobilinogen metabolism.

Authors:  U A Meyer; L J Strand; M Doss; A C Rees; H S Marver
Journal:  N Engl J Med       Date:  1972-06-15       Impact factor: 91.245

6.  Delta-aminolevulinic acid dehydratase activity in circulating blood cells. A sensitive laboratory test for the detection of childhood lead poisoning.

Authors:  J B Weissberg; F Lipschutz; F A Oski
Journal:  N Engl J Med       Date:  1971-03-18       Impact factor: 91.245

7.  A micro-sampling method for the rapid determination of lead in blood by atomic-absorption spectrophotometry.

Authors:  H T Delves
Journal:  Analyst       Date:  1970-05       Impact factor: 4.616

8.  Enzymatic studies on erythroid differentiation and proliferation.

Authors:  K Nakao; S Sassa; O Wada; F Takaku
Journal:  Ann N Y Acad Sci       Date:  1968-03-29       Impact factor: 5.691
  8 in total
  35 in total

1.  Acute intermittent porphyria in childhood: a neglected diagnosis?

Authors:  M Kreimer-Birnbaum; R M Bannerman
Journal:  Arch Dis Child       Date:  1975-06       Impact factor: 3.791

2.  Split dose studies on the erythropoietic effects of cadmium.

Authors:  G R Hogan; S L Razniak
Journal:  Bull Environ Contam Toxicol       Date:  1992-06       Impact factor: 2.151

3.  Lead-induced anemia: dose-response relationships and evidence for a threshold.

Authors:  J Schwartz; P J Landrigan; E L Baker; W A Orenstein; I H von Lindern
Journal:  Am J Public Health       Date:  1990-02       Impact factor: 9.308

4.  Detection of sub-clinical lead toxicity in monocasters.

Authors:  B D Kumar; K Krishnaswamy
Journal:  Bull Environ Contam Toxicol       Date:  1995-06       Impact factor: 2.151

5.  [Measure of lead exposure in a group of young girls].

Authors:  P Hotz; H J Russenberger; H U Wanner
Journal:  Soz Praventivmed       Date:  1977 May-Jun

6.  Occupational lead poisoning, animal deaths, and environmental contamination at a scrap smelter.

Authors:  R J Levine; R M Moore; G D McLaren; W F Barthel; P J Landrigan
Journal:  Am J Public Health       Date:  1976-06       Impact factor: 9.308

7.  Pilot study of mitochondrial bioenergetics in subjects with acute porphyrias.

Authors:  Natalia Dixon; Ting Li; Brandon Marion; Denise Faust; Stephen Dozier; Anthony Molina; Sean Rudnick; Herbert L Bonkovsky
Journal:  Mol Genet Metab       Date:  2019-05-20       Impact factor: 4.797

8.  Response of free erythrocyte porphyrin and urinary delta-aminolevulinic acid in men and women moderately exposed to lead.

Authors:  H A Roels; R R Lauwerys; J P Buchet; M T Vrelust
Journal:  Int Arch Arbeitsmed       Date:  1975

9.  Studies in porphyria. VII. Induction of uroporphyrinogen-I synthase and expression of the gene defect of acute intermittent porphyria in mitogen-stimulated human lymphocytes.

Authors:  S Sassa; G L Zalar; A Kappas
Journal:  J Clin Invest       Date:  1978-02       Impact factor: 14.808

10.  The relationship between zinc protoporphyrin (ZPP) and "free" erythrocyte protoporphyrin (FEP) in lead-exposed individuals.

Authors:  V Karacić; D Prpić-Majić; S Telisman
Journal:  Int Arch Occup Environ Health       Date:  1980       Impact factor: 3.015
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