Literature DB >> 4506090

Stereochemistry of a curare alkaloid: O,O',N-trimethyl-d-tubocurarine.

H M Sobell, T D Sakore, S S Tavale, F G Canepa, P Pauling, T J Petcher.   

Abstract

The three-dimensional structure of O,O',N-trimethyl-d-tubocurarine, a neuromuscular blocking agent, has been determined by x-ray crystallography. This may help to provide insight into its pharmacologic action.

Entities:  

Mesh：

Substances：

Year:  1972        PMID： 4506090      PMCID： PMC426902          DOI： 10.1073/pnas.69.8.2212

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  8 in total

1.  ISOLATION OF NEUROTOXINS FROM THE VENOM OF BUNGARUS MULTICINCTUS AND THEIR MODES OF NEUROMUSCULAR BLOCKING ACTION.

Authors:  C C CHANG; C Y LEE
Journal:  Arch Int Pharmacodyn Ther       Date:  1963-07-01

2.  A study of curare action with an electrical micromethod.

Authors:  L DEL CASTILLO; B KATZ
Journal:  Proc R Soc Lond B Biol Sci       Date:  1957-05-07

3.  Acetylcholine receptors in muscle fibres.

Authors:  R Miledi; L T Potter
Journal:  Nature       Date:  1971-10-29       Impact factor: 49.962

4.  Influence of denervation on localization of neurotoxins from clapid venoms in rat diaphragm.

Authors:  C Y Lee; L F Tseng; T H Chiu
Journal:  Nature       Date:  1967-09-09       Impact factor: 49.962

Review 5.  Structure and activity of acetylcholine.

Authors:  W H Beers; E Reich
Journal:  Nature       Date:  1970-12-05       Impact factor: 49.962

6.  Isolation of the cholinergic receptor protein of Torpedo electric tissue.

Authors:  R Miledi; P Molinoff; L T Potter
Journal:  Nature       Date:  1971-02-19       Impact factor: 49.962

7.  Stereochemistry of actinomycin--DNA binding.

Authors:  H M Sobell; S C Jain; T D Sakore; C E Nordman
Journal:  Nat New Biol       Date:  1971-06-16

8.  Use of a snake venom toxin to characterize the cholinergic receptor protein.

Authors:  J P Changeux; M Kasai; C Y Lee
Journal:  Proc Natl Acad Sci U S A       Date:  1970-11       Impact factor: 11.205
  8 in total
  7 in total

1.  Conformational analysis of d-tubocurarine: implications for minimal dimensions of its binding site within ion channels.

Authors:  B S Zhorov; N B Brovtsyna
Journal:  J Membr Biol       Date:  1993-07       Impact factor: 1.843

Review 2.  End-plate acetylcholine receptor: structure, mechanism, pharmacology, and disease.

Authors:  Steven M Sine
Journal:  Physiol Rev       Date:  2012-07       Impact factor: 37.312

3.  Curariform antagonists bind in different orientations to acetylcholine-binding protein.

Authors:  Fan Gao; Nina Bern; Alicia Little; Hai-Long Wang; Scott B Hansen; Todd T Talley; Palmer Taylor; Steven M Sine
Journal:  J Biol Chem       Date:  2003-04-07       Impact factor: 5.157

4.  The actions of tubocurarine at the frog neuromuscular junction.

Authors:  D Colquhoun; F Dreyer; R E Sheridan
Journal:  J Physiol       Date:  1979-08       Impact factor: 5.182

5.  Symmetry in drug molecules [proceedings].

Authors:  P Chrusciel; P J Goodford
Journal:  Br J Pharmacol       Date:  1979-05       Impact factor: 8.739

Review 6.  Neuromuscular transmission and its pharmacological blockade. Part 1: Neuromuscular transmission and general aspects of its blockade.

Authors:  L H Booij
Journal:  Pharm World Sci       Date:  1997-02

7.  Biliary excretion of some diquaternary ammonium cations in the rat, guinea pig and rabbit.

Authors:  R D Hughes; P Millburn; R T Williams
Journal:  Biochem J       Date:  1973-12       Impact factor: 3.857
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.