| Literature DB >> 4504380 |
P Gonzalez-Porque, J L Strominger.
Abstract
A cofactor needed for the reduction of CDP-4-keto-6-deoxy-D-glucose to CDP-4-keto-3,6-dideoxy D-glucose has been detected and purified. Its spectra in neutral, acid, and basic solutions, its behavior on thin-layer chromatography, and other properties led to its identification as pyridoxamine-5'-phosphate. Moreover, authentic pyridoxamine-5'-phosphate substituted for the purified cofactor with about the same specific activity. Other vitamin B(6) derivatives did not stimulate the reaction, and inhibition was observed with some of them.Entities:
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Year: 1972 PMID： 4504380 PMCID： PMC426762 DOI： 10.1073/pnas.69.6.1625
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205