| Literature DB >> 4502936 |
C Paoletti, G Riou, J Pairault.
Abstract
Circular dimers and higher oligomers of mitochondrial DNA have previously only been described in tumor cells. This work demonstrates that such oligomers are also consistently found in a relatively high content (10-37% in weight) in nonmalignant human and beef thyroid glands. Therefore, these forms cannot be assumed to be specific for malignancy, even if they could be related to it in some instances.Entities:
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Year: 1972 PMID： 4502936 PMCID： PMC426578 DOI： 10.1073/pnas.69.4.847
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205