Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Human placental 15-hydroxyprostaglandin dehydrogenase.

Literature DB >> 4501572

Human placental 15-hydroxyprostaglandin dehydrogenase.

Abstract

Normal, term, human placentas are a rich source of a 15-hydroxyprostaglandin dehydrogenase. The enzyme is extremely labile, and partial purification could be achieved only after stabilization with glycerol. The instability of the enzyme and its K(m) for NAD are indications that it is different from the 15-hydroxyprostaglandin dehydrogenase isolated from swine lung. Human placental tissue should provide a very useful source from which large amounts of highly purified 15-hydroxyprostaglandin dehydrogenase may be obtained.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 1972 PMID： 4501572 PMCID： PMC426500 DOI： 10.1073/pnas.69.3.533

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

8 in total

4. The distribution of 15-hydroxy prostaglandin dehydrogenase and prostaglandin-delta 13-reductase in tissues of the swine.

Authors: E Anggård; C Larsson; B Samuelsson
Journal: Acta Physiol Scand Date: 1971-03

4 in total

4. In vitro activity of nicotinamide adenine dinucleotide- and nicotinamide adenine dinucleotide phosphate-linked 15-hydroxyprostaglandin dehydrogenases in placentas from normotensive and preeclamptic/eclamptic pregnancies.

Authors: J Jarabak; J D Watkins; M Lindheimer
Journal: J Clin Invest Date: 1987-10 Impact factor: 14.808

4 in total

Human placental 15-hydroxyprostaglandin dehydrogenase.

1. On the metabolism of prostaglandin F-2-alpha in female subjects.

2. Metabolism of prostaglandin E1 in human plasma, uterus and placenta, in swine ovary and in rat testicle.

3. 15-Hydroxy-prostanoate dehydrogenase. Prostaglandins as substrates and inhibitors.

4. The distribution of 15-hydroxy prostaglandin dehydrogenase and prostaglandin-delta 13-reductase in tissues of the swine.

5. The role of prostaglandins in human parturition.

6. Prostaglandin content of amniotic fluid during pregnancy and labour.

7. The biological activities of three metabolites of prostaglandin E 1.

8. Prostaglandins: their disappearance from and release into the circulation.

1. Changes of the prostaglandin F2a metabolism in early human placenta.

2. Immunologic and genetic factors influencing reproduction. A review.

Review 3. Formation and degradation of prostaglandins in the lung.

4. In vitro activity of nicotinamide adenine dinucleotide- and nicotinamide adenine dinucleotide phosphate-linked 15-hydroxyprostaglandin dehydrogenases in placentas from normotensive and preeclamptic/eclamptic pregnancies.